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- 3D shape prior active contours for an automatic segmentation of a patient specific femur from a CT scanPublication . Almeida, D.; Folgado, J.; Fernandes, P.R.; Ruben, RuiThe following paper describes a novel approach to a medical image segmentation problem. The fully automated computational procedure receives as input images from CT scan exams of the human femur and returns a three dimensional representation of the bone. This patient specific iterative approach is based in 3D active contours without edges, implemented over a level set framework, on which the evolution of the contour depends on local image parameters which can easily be defined by the user but also on a priori information about the volume to segment. This joint approach will lead to an optimal solution convergence of the iterative method. The resulting point cloud can be an excellent starting point for a Finite Element mesh generation and analysis or the basis for a stereolitography for example.
- Computational Resource Management for Video Coding in Mobile EnvironmentsPublication . Correa, Guilherme; Assunção, Pedro; Agostini, Luciano; Cruz, Luis A. da SilvaThe increase of computational resources in mobile devices and the availability of reliable communication infrastructures provide support for acquisition, display, coding/decoding and transmission of high-resolution video in a broad set of equipment such as tablets and smartphones. Nevertheless, real-time video encoding and decoding is still a challenge in such computing environments, especially when considering the amount of computational resources required by state-of-the-art video coding standards. Moreover, battery technologies did not evolve as much as desired, which makes power consumption minimization an important issue for the mobile devices industry and users. Therefore, in current mobile systems, the available computational resources along with battery-life are responsible for imposing significant limitations on mobile real-time multimedia communications. This chapter presents an overview of the state-of-the-art research on management of computational resources for video encoding systems in mobile communications equipment. A review on computational complexity analysis of both H.264/AVC and HEVC video coding standards is presented, followed by a description of current methods for modelling, reducing and controlling the expenditure of computational resources on these video codecs. Finally, future trends on computational complexity management for video codecs implemented on power-constrained devices are lined out.
- Design of Radio-Frequency Integrated CMOS Discrete Tuning Varactors Using the Particle Swarm Optimization AlgorithmPublication . Pires, E. J. Solteiro; Mendes, Luís; Oliveira, P. B. de Moura; Machado, J. A. Tenreiro; Vaz, João C.; Rosário, Maria J.This paper presents an automated design procedure of radio- frequency integrated CMOS discrete tuning varactors (RFDTVs). This new method use the maximin and the particle swarm optimization (PSO) algorithms to promote well distributed non-dominated fronts in the parameters space when a single-objective function is optimized. The fitness function used in the search tool is proportional to the RFDTV quality factor. The outcome of the automated design method comprises a set of RFDTV circuits, all having the same maximum performance. Each solution, which corresponds to one RFDTV circuit, is defined by the number of cells and by the circuit components values. This approach allows the designer to choose among several possible circuits the one that is easier to implement in a given CMOS process. To validate the effectiveness of the synthesis procedure proposed in this paper (PSO-method) comparisons with a design method based on genetic algorithms (GA-method) are presented. A 0.18 μm CMOS radio-frequency binary-weighted differential switched capacitor array (RFDSCA) was designed and implemented (the RFDSCA is one of the possible topologies of the RFDTVs). The results show that both design methods are in very good agreement. However, the PSO technique outperforms the GA-method in the design procedure run time taken to accomplish the same performance results.
- Design Optimization of Radio Frequency Discrete Tuning VaractorsPublication . Moreira Mendes, Luís Miguel; Pires, Eduardo J. Solteiro; Oliveira, Paulo B. de Moura; Machado, José A. Tenreiro; Ferreira, Nuno M. Fonseca; Vaz, João Caldinhas; Rosário, Maria J.This work presents a procedure to automate the design of Si-integrated radio frequency (RF) discrete tuning varactors (RFDTVs). The synthesis method, which is based on evolutionary algorithms, searches for optimum performance RF switched capacitor array circuits that fulfill the design restrictions. The design algorithm uses the ε-dominance concept and the maximin sorting scheme to provide a set of different solutions (circuits) well distributed along an optimal front in the parameter space (circuit size and component values). Since all the solutions present the same performance, the designer can select the circuit that is best suited to be implemented in a particular integration technology. To assess the performance of the synthesis procedure, several RFDTV circuits, provided by the algorithm, were designed and simulated using a 0.18μm CMOS technology and the Cadence Virtuoso Design Platform. The comparisons between the algorithm and circuit simulation results show that they are very close,poi ting out that the proposed design procedure is a powerful design tool.
- Electrospinning for Medical ApplicationsPublication . Song, Wenhui; Mitchell, Geoffrey R.; Burugapalli, KrishnaThere is a natural connection between a variety of electrospun fibres and biomedical applications. The most commonly quoted application of electrospun fibres is their use as scaffolds in tissue engineering for regenerative medicine. There are also many other applications, which include drug delivery systems, membrane systems and analytical functionality. This chapter identifies the key challenges in each of these topics, as well as the particular role of electrospun fibres in addressing these challenges.
- A Face Attention Technique for a Robot Able to Interpret Facial ExpressionsPublication . Simplício, Carlos; Prado, José; Dias, JorgeAutomatic facial expressions recognition using vision is an important subject towards human-robot interaction. Here is proposed a human face focus of attention technique and a facial expressions classifier (a Dynamic Bayesian Network) to incorporate in an autonomous mobile agent whose hardware is composed by a robotic platform and a robotic head. The focus of attention technique is based on the symmetry presented by human faces. By using the output of this module the autonomous agent keeps always targeting the human face frontally. In order to accomplish this, the robot platform performs an arc centered at the human; thus the robotic head, when necessary, moves synchronized. In the proposed probabilistic classifier the information is propagated, from the previous instant, in a lower level of the network, to the current instant. Moreover, to recognize facial expressions are used not only positive evidences but also negative.
- Photocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by StereolithographyPublication . Pereira, Rúben F.; Bártolo, Paulo J.Stereolithography is an additive technique that produces three-dimensional (3D) solid objects using a multi-layer procedure through the selective photoinitiated curing reaction of a liquid photosensitive material. Stereolithographic processes have been widely employed in Tissue Engineering for the fabrication of temporary constructs, using natural and synthetic polymers, and polymer-ceramic composites. These processes allow the fabrication of complex structures with a high accuracy and precision at physiological temperatures, incorporating cells and growth factors without significant damage or denaturation. Despite recent advances on the development of novel biomaterials and biocompatible crosslinking agents, the main limitation of these techniques are the lack number of available photocrosslinkable materials, exhibiting appropriate biocompatibility and biodegradability. This chapter gives an overview of the current state-of-art of materials and stereolithographic techniques to produce constructs for tissue regeneration, outlining challenges for future research.
- PrefacePublication . Fernandes, Paulo Rui; Bártolo, Paulo JorgeThis book is a contribution for Tissue Engineering seen as multidisciplinary field involving scientists from different backgrounds like medicine, chemistry, material science, engineering and biology with a focus on the development of mathematical methods that are quite relevant to understand cell biology and human tissues as well to model, design and fabricate optimized and smart scaffolds.
- PrefacePublication . Almeida, Henrique A.; Vasco, Joel C.The “Progress in Digital and Physical Manufacturing” book contains keynotes and papers presented at the first International Conference on Progress in Digital and Physical Manufacturing (ProDPM’19), organized by the School of Technology and Management (ESTG) of the Polytechnic Institute of Leiria (IPLeiria), from October 2 to 4, 2019. This international conference aims to provide a major international forum for the scientific exchange of multi-disciplinary and inter-organizational aspects performed by academics, researchers, and industrial partners in order to exchange ideas in the field of digital and physical manufacturing and related areas. It represents a significant contribution to the current advances in industrial digital and physical manufacturing issues as it contains topical research in this field.
- Recent Advances in Additive BiomanufacturingPublication . Pereira, Rúben Filipe Brás; Bartolo, PauloThe principles of tissue engineering and regenerative medicine have been used for the development of innovative medical therapies for engineering tissues and organs. These therapies involve the use of biomaterials, cells, and biologically active molecules, according to two fundamental strategies: the top-down and bottom-up approaches. Top-down approaches, which are the most commonly used, involve the implantation of porous scaffolds, with or without living cells and bioactive agents, into the defect site in the patient. In these approaches, scaffolds act as temporary templates for the seeded cells, mimicking the properties of the native extracellular matrix and providing an adequate environment for the growth of the new tissue. Scaffolds can be produced by using either conventional or additive techniques, resulting in structures with different levels of porosity, pore size, interconnectivity, and spatial distribution. Additive biomanufacturing techniques allow significantly more control over the scaffold characteristics (e.g., architecture, porosity, permeability, etc.), enabling the automatic and reproducible fabrication of scaffolds in a wide range of polymeric, ceramic, and composite materials. Some of these techniques also allow the fabrication of constructs encapsulating living cells. This chapter describes the most recent advances in the top-down approach to fabricate scaffolds for tissue regeneration, presenting the most important additive biomanufacturing techniques and processable materials. Future perspectives in the field and challenges for future research are also discussed.
