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Photocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by Stereolithography

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Photocrosslinkable materials for the fabrication of tissue-engineered constructs by stereolithography.pdfStereolithography is an additive technique that produces three-dimensional (3D) solid objects using a multi-layer procedure through the selective photoinitiated curing reaction of a liquid photosensitive material. Stereolithographic processes have been widely employed in Tissue Engineering for the fabrication of temporary constructs, using natural and synthetic polymers, and polymer-ceramic composites. These processes allow the fabrication of complex structures with a high accuracy and precision at physiological temperatures, incorporating cells and growth factors without significant damage or denaturation. Despite recent advances on the development of novel biomaterials and biocompatible crosslinking agents, the main limitation of these techniques are the lack number of available photocrosslinkable materials, exhibiting appropriate biocompatibility and biodegradability. This chapter gives an overview of the current state-of-art of materials and stereolithographic techniques to produce constructs for tissue regeneration, outlining challenges for future research.1.37 MBAdobe PDF Ver/Abrir

Orientador(es)

Resumo(s)

Stereolithography is an additive technique that produces three-dimensional (3D) solid objects using a multi-layer procedure through the selective photoinitiated curing reaction of a liquid photosensitive material. Stereolithographic processes have been widely employed in Tissue Engineering for the fabrication of temporary constructs, using natural and synthetic polymers, and polymer-ceramic composites. These processes allow the fabrication of complex structures with a high accuracy and precision at physiological temperatures, incorporating cells and growth factors without significant damage or denaturation. Despite recent advances on the development of novel biomaterials and biocompatible crosslinking agents, the main limitation of these techniques are the lack number of available photocrosslinkable materials, exhibiting appropriate biocompatibility and biodegradability. This chapter gives an overview of the current state-of-art of materials and stereolithographic techniques to produce constructs for tissue regeneration, outlining challenges for future research.

Descrição

EISBN - 9789400770737
Volume 31, Pages 149 - 178
https://www.researchgate.net/publication/278653255_Photocrosslinkable_Materials_for_the_Fabrication_of_Tissue-Engineered_Constructs_by_Stereolithography

Palavras-chave

Stereolithography Tissue engineering biomaterials fabrication photocrosslinkable materials tissue regeneration

Contexto Educativo

Citação

Pereira, R.F., Bártolo, P.J. (2014). Photocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by Stereolithography. In: Fernandes, P., Bartolo, P. (eds) Tissue Engineering. Computational Methods in Applied Sciences, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7073-7_8.

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Editora

Springer Nature

Licença CC

Sem licença CC

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