Browsing by Issue Date, starting with "2020"
Now showing 1 - 10 of 697
Results Per Page
Sort Options
- A SISTÉMICA FAMILIAR NO CUIDADO DE ENFERMAGEM CENTRADO NA FAMÍLIA IMPACTO DE UM PROGRAMA DE FORMAÇÃOPublication . Henriques, Carolina; Jordão, Tânia Fernanda Mesquita da SilvaA enfermagem de saúde familiar é uma disciplina recente, com evolução nas últimas décadas. Os estudos nesta área indiciam que a abordagem sistémica da família não é prática habitual pelos profissionais. Pretende-se com este estudo conhecer a perceção dos conceitos de família e de enfermagem de saúde familiar, avaliar os conhecimentos sobre sistémica familiar e avaliar o impacto de um programa de formação centrado nos conhecimentos sobre sistémica familiar no cuidado à família em oito enfermeiros que integram uma Unidade de Saúde Familiar de Portugal. Utilizou-se a aplicação de questionário autoadministrado sobre o mesmo grupo de sujeitos, em dois momentos: Uma avaliação inicial e uma avaliação após o programa de formação. Verificou-se o aumento dos conhecimentos nos enfermeiros sujeitos ao programa de formação, validando a hipótese de investigação: Existem diferenças estatisticamente significativas nos conhecimentos sobre sistémica familiar no cuidado à família, dos enfermeiros que integram uma Unidade de Saúde Familiar, antes e após a implementação de um Programa de Formação, destacando a necessidade e importância de desenvolver e implementar programas de formação neste âmbito para profissionais de enfermagem.
- Dietitians and Nutritionists Behaviour on Social Media: A Scoping Literature ReviewPublication . Saboia, Inga; Almeida, Ana Margarida Pisco; Sousa, Pedro; Pernencar, C.At its present state, Social Media (SM) is an important stage to promote user participation, acting as an open space for the discussion of a multitude of fields, one of which being health. Professionals, like Registered Nutritionists and Dietitians (RNDs), whose access to media was traditionally more restricted, are also more engaged in this new context, creating a new scenario. To better understand how is this group of professionals using social media to communicate with their audiences is the main objective of this study. To approach this topic, a mapping was conducted, followed by a presentation of the summary of the evidence discovered: RDNs demographic and professional profile; their most used social media tools; the reasons why they use social media; their common behaviours and attitudes, as well as a review of the gaps and shortcomings in the literature. A literature review, using a structured approach was also conducted. 2877 works were screened, but only 8 were associated with answers. Of these 8, there were 2 studies that partially presented a quantitative analysis. Results show lacks in consolidated studies that can be used to support the creation of knowledge in this field. This lead to conclude that research about social media usage by nutritionist, at present, remains in a nascent stage and requires further studies.
- Sphaerococcus coronopifolius bromoterpenes as potential cancer stem cell-targeting agentsPublication . Alves, Celso; Serrano, Eurico; Silva, Joana; Rodrigues, Carlos; Pinteus, Susete; Gaspar, Helena; Botana, Luis M.; Alpoim, Maria C.; Pedrosa, RuiCancer is one of the major threats to human health and, due to distinct factors, it is expected that its incidence will increase in the next decades leading to an urgent need of new anticancer drugs development. Ongoing experimental and clinical observations propose that cancer cells with stem-like properties (CSCs) are involved on the development of lung cancer chemoresistance. As tumour growth and metastasis can be controlled by tumourassociated stromal cells, the main goal of this study was to access the antitumor potential of five bromoterpenes isolated from Sphaerococcus coronopifolius red alga to target CSCs originated in a co-culture system of fibroblast and lung malignant cells. Cytotoxicity of compounds (10–500 μM; 72 h) was evaluated on monocultures of several malignant and non-malignant cells lines (HBF, BEAS-2B, RenG2, SC-DRenG2) and the effects estimated by MTT assay. Co-cultures of non-malignant human bronchial fibroblasts (HBF) and malignant human bronchial epithelial cells (RenG2) were implemented and the compounds ability to selectively kill CSCs was evaluated by sphere forming assay. The interleucine-6 (IL-6) levels were also determined as cytokine is crucial for CSCs. Regarding the monocultures results bromosphaerol selectively eliminated the malignant cells. Both 12S-hydroxy-bromosphaerol and 12R-hydroxy-bromosphaerol steroisomers were cytotoxic towards non-malignant bronchial BEAS-2B cell line, IC50 of 4.29 and 4.30 μM respectively. However, none of the steroisomers induced damage in the HBFs. As to the co-cultures, 12R-hydroxy-bromosphaerol revealed the highest cytotoxicity and ability to abrogate the malignant stem cells; however its effects were IL-6 independent. The results presented here are the first evidence of the potential of these bromoterpenes to abrogate CSCs opening new research opportunities. The 12R-hydroxy-bromosphaerol revealed to be the most promising compound to be test in more complex living models.
- Tradução, adaptação cultural e validação do Meaning in Suffering Test para português europeuPublication . Kraus, Teresa; Capela, Susana; Rodrigues, Manuel; Dixe, Maria dos AnjosAs diferenças paradoxais identificadas entre a forma como as pessoas experienciam a dor, independente da sua intensidade, e o sofrimento a ela associado, relacionam-se com os sistemas de crenças e valores.
- Crosslinked nanocomposite sodium alginate-based membranes with titanium dioxide for the dehydration of isopropanol by pervaporationPublication . Premakshi, P. G.; Kariduraganavar, Mahadevappa Y.; Mitchell, GeoffreySodium alginate (NaAlg) based membranes were prepared using a solution technique, crosslinked with poly(styrene sulfonic acid-co-maleic acid) (PSSA-co-MA). Subsequently, the membranes were modified by the incorporation of 0, 10, 20, 30 and 40% w/w of titanium dioxide with respect to sodium alginate. The membranes thus obtained were designated as M, M-1, M-2, M-3 and M-4, respectively. An equilibrium swelling experiment was performed using dfferent compositions of the water and isopropanol mixtures. Subsequently, we used a pervaporation cell fitted with each membrane in order to evaluate the extent of the pervaporation dehydration of isopropanol. Among the membranes studied, the membranes containing 40 mass% of titanium dioxide exhibited the highest separation factor() of 24,092, with a flux(J) of 18.61x10-² kg/m².h at 30ºC for 10 mass%w/w of water in the feed. The total flux and the flux of water were found to overlap with each other, indicating that these membranes can be e ectively used to break the azeotropic point of water–isopropanol mixtures. The results clearly indicate that these nanocomposite membranes exhibit an excellent performance in the dehydration of isopropanol. The activation energy values obtained for the water permeation were significantly lower than those of the isopropanol permeation, underlining that these membranes have a high separation ability for the water isopropanol system. The estimated activation energies for total permeation (EP) and total di usion (ED) values ranged between 10.60 kJ.mol-¹ and 3.96 kJ.mol-¹, and 10.76 kJ.mol-¹ and 4.29 kJ.mol-¹, respectively. The negative change in the enthalpy values for all the membranes indicates that sorption was mainly dominated by Langmuir’s mode of sorption.
- The value of choroidal thickness in diabetic macular oedema is contradictoryPublication . Campos, António; Campos, Elisa J.; Martins, João; Ambrósio, António Francisco; Silva, Rufino
- The impact of the European Wine City 2018: Torres Vedras / Alenquer (CEV) in the local stakeholdersPublication . Ramos, Dulcineia; Penetra, RuiEvents can have a very positive impact on the image of a destination. Wine tourism events can be distinguished as holders of special and peculiar characteristics that bring us to "authenticity" and experimentation. These are essential criteria for the success of a tourism product. In this sequence, the objective will be to determine the Impact of the European Wine City 2018 - Torres Vedras / Alenquer (CEV). The main goals of this investigation will be to determine the general impact of the European Wine City 2018 - Torres Vedras / Alenquer not only through the application of surveys to local agents and partners, but also through the evaluation of the associated media clipping.
- Financial literacy perception scale for the Portuguese populationPublication . Tavares, F.O.; Santos, E.This study aims to propose and validate a financial literacy perception scale for the Portuguese population. The utilized methodology was quantitative, based on a two-part questionnaire survey. The first part studies the sociodemographic profile and the second part evaluates the respondent's perception of financial literacy. The sample consisted of 830 Portuguese individuals, over 18 years old. The main results of this study demonstrate that the financial literacy perception scale presents a tri-factorial structure with satisfactory validity and reliability levels. The three obtained factors are 1-2 years financial planning and goals, long term savings and an affinity for numerical calculation. This study contributes to the increase of scientific knowledge in the field of financial literacy, to the assistance of financial education policymakers in the reformulation of their policies and to the creation of tools to help consumer financial behavior.
- Os meios extrajudiciais de resolução de conflitos no quadro do direito de acesso à justiça e a Convenção dos Direitos das Pessoas com DeficiênciaPublication . Monteiro, Susana Sardinha; Cebola, Cátia Marques
- Quality changes during thermal processing of two mixed formulas of fruits and vegetables pulpsPublication . Gonçalves, Elsa M.; Raposo, Isa; Pinheiro, Joaquina; Alegria, Carla; Moldão, Margarida; Abreu, MartaThe present work aimed to evaluate, through thermal degradation kinetics (80 °C to 98 °C in time intervals of 0.5 to 25 min), the effects of different thermal treatments on the biochemical, physicochemical, sensory and microbiological parameters of two mixed fruit and vegetable pulps, a yellow and a red one. The evaluated fruit and vegetable pulps resulted from the mixture of different fruits and vegetables proportions (pineapple, beetroot, strawberry and lemon juice) added to a 50% (p/p) pear-based pulp to maximize their bioactivity, physicochemical stability and sensorial acceptance. Evaluated quality parameters included the determination of peroxidase activity (POD), pH, soluble solids content (SSC), total phenolic content (TPC), CIELab colour, sensory evaluation (colour, taste and aroma) and total mesophilic aerobic counts (TAPC). Regarding heat treatments optimization for both pulps with lower pH, it was concluded that higher temperature treatments (90 to 98 °C) applied over a shorter time (less than 5 min) were more effective to inactivate POD, to reduce the initial microbial load (>2 log10 cycles) and to maximize sensorial attributes. In both mix pulps, total phenolic content (TPC) was not significantly influenced by the different applied time-temperature binomials. From the degradation kinetic models and as an example, it was possible to conclude that POD followed a 1st order kinetic, where the temperature effect was well fitted to the Arrhenius equation. The results allowed to obtain optimized time-temperature binomials for each pulp to simultaneously achieve POD enzyme inactivation, microbial reduction, and maximization of quality parameters relatively to fresh pulps, 90 °C/5 min and 98 °C/2.5 min, for the yellow pulp and red pulp, respectively.