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Phytopharmacological strategies in the management of type 2 diabetes Mellitus

dc.contributor.authorDuarte, Ana M.
dc.contributor.authorGuarino, Maria P.
dc.contributor.authorBarroso, Sonia
dc.contributor.authorGil, Maria M
dc.date.accessioned2020-08-17T09:50:24Z
dc.date.available2020-08-17T09:50:24Z
dc.date.issued2020
dc.descriptionThe authors thank FCT, Portugal, for financial support (UID/MAR/04292/2019). This work was also supported by project SmartBioR (CENTRO-01-0145-FEDER-000018, Integrated Programme SR&TD co-funded by Centro 2020 program, Portugal 2020, European Union, through the European Regional Development Fund).pt_PT
dc.description.abstractType 2 Diabetes Mellitus (T2DM) is a chronic disease which corresponds to 90% of the worldwide cases of diabetes, mainly due to epigenetic factors such as unhealthy lifestyles. First line therapeutic approaches are based on lifestyle changes, most of the time complemented with medication mostly associated with several side e ects and high costs. As a result, the scientific community is constantly working for the discovery and development of natural therapeutic strategies that provide lower financial impact and minimize side e ects. This review focus on these nature-based therapeutic strategies for prevention and control of T2DM, with a special emphasis on natural compounds that present pharmacological activity as dipeptidyl peptidase-4 (DPP4), alpha-amylase, alpha-glucosidase, lipase, and protein tyrosine phosphatase 1B (PTP1B) inhibitors.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDuarte, A.M.; Guarino, M.P.; Barroso, S.; Gil, M.M. Phytopharmacological Strategies in the Management of Type 2 Diabetes Mellitus. Foods 2020, 9, 271.pt_PT
dc.identifier.doi10.3390/foods9030271pt_PT
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10400.8/5086
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationMARE - Marine and Environmental Sciences Centre
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectType 2 diabetes mellituspt_PT
dc.subjectPhytopharmacologypt_PT
dc.subjectDipeptidyl peptidase-4 (DPP4)pt_PT
dc.subjectAlpha-amylasept_PT
dc.subjectAlpha-glucosidasept_PT
dc.subjectLipasept_PT
dc.subjectProtein tyrosine phosphatase 1B (PTP1B)pt_PT
dc.titlePhytopharmacological strategies in the management of type 2 diabetes Mellituspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMARE - Marine and Environmental Sciences Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMAR%2F04292%2F2019/PT
oaire.citation.issue3pt_PT
oaire.citation.titleFoodspt_PT
oaire.citation.volume9pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCardoso Duarte
person.familyNameGuarino
person.familyNameDuarte Barroso
person.familyNameGil
person.givenNameAna Marta
person.givenNameMaria Pedro
person.givenNameSónia
person.givenNameMaria M
person.identifierH-7791-2012
person.identifier.ciencia-idE41E-EBE9-6C93
person.identifier.ciencia-idF21A-BD01-2D52
person.identifier.ciencia-id2C11-7528-F0B2
person.identifier.ciencia-id7313-A289-DF48
person.identifier.orcid0000-0001-7103-3924
person.identifier.orcid0000-0001-6079-1105
person.identifier.orcid0000-0002-6152-265X
person.identifier.orcid0000-0002-8008-9839
person.identifier.ridB-5594-2015
person.identifier.ridO-4858-2015
person.identifier.scopus-author-id56348477000
person.identifier.scopus-author-id13404922100
person.identifier.scopus-author-id12785024700
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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