A carregar...
Publicação
Phytopharmacological strategies in the management of type 2 diabetes Mellitus
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 609.36 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Type 2 Diabetes Mellitus (T2DM) is a chronic disease which corresponds to 90% of the
worldwide cases of diabetes, mainly due to epigenetic factors such as unhealthy lifestyles. First line therapeutic approaches are based on lifestyle changes, most of the time complemented with medication mostly associated with several side e ects and high costs. As a result, the scientific community is constantly working for the discovery and development of natural therapeutic strategies that provide lower financial impact and minimize side e ects. This review focus on these nature-based therapeutic
strategies for prevention and control of T2DM, with a special emphasis on natural compounds that present pharmacological activity as dipeptidyl peptidase-4 (DPP4), alpha-amylase, alpha-glucosidase, lipase, and protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Descrição
The authors thank FCT, Portugal, for financial support (UID/MAR/04292/2019). This work was also supported by project SmartBioR (CENTRO-01-0145-FEDER-000018, Integrated Programme SR&TD co-funded by Centro 2020 program, Portugal 2020, European Union, through the European Regional Development Fund).
Palavras-chave
Type 2 diabetes mellitus Phytopharmacology Dipeptidyl peptidase-4 (DPP4) Alpha-amylase Alpha-glucosidase Lipase Protein tyrosine phosphatase 1B (PTP1B)
Contexto Educativo
Citação
Duarte, A.M.; Guarino, M.P.; Barroso, S.; Gil, M.M. Phytopharmacological Strategies in the Management of Type 2 Diabetes Mellitus. Foods 2020, 9, 271.
Editora
MDPI