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Photocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by Stereolithography

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datacite.subject.fosEngenharia e Tecnologia::Engenharia Química
datacite.subject.fosCiências Naturais::Ciências da Computação e da Informação
datacite.subject.fosEngenharia e Tecnologia::Engenharia Civil
datacite.subject.fosEngenharia e Tecnologia::Engenharia Eletrotécnica, Eletrónica e Informática
datacite.subject.fosCiências Naturais::Matemáticas
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorPereira, Rúben F.
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2025-06-30T15:38:12Z
dc.date.available2025-06-30T15:38:12Z
dc.date.issued2014
dc.descriptionEISBN - 9789400770737
dc.descriptionVolume 31, Pages 149 - 178
dc.descriptionhttps://www.researchgate.net/publication/278653255_Photocrosslinkable_Materials_for_the_Fabrication_of_Tissue-Engineered_Constructs_by_Stereolithography
dc.description.abstractStereolithography is an additive technique that produces three-dimensional (3D) solid objects using a multi-layer procedure through the selective photoinitiated curing reaction of a liquid photosensitive material. Stereolithographic processes have been widely employed in Tissue Engineering for the fabrication of temporary constructs, using natural and synthetic polymers, and polymer-ceramic composites. These processes allow the fabrication of complex structures with a high accuracy and precision at physiological temperatures, incorporating cells and growth factors without significant damage or denaturation. Despite recent advances on the development of novel biomaterials and biocompatible crosslinking agents, the main limitation of these techniques are the lack number of available photocrosslinkable materials, exhibiting appropriate biocompatibility and biodegradability. This chapter gives an overview of the current state-of-art of materials and stereolithographic techniques to produce constructs for tissue regeneration, outlining challenges for future research.eng
dc.description.sponsorshipThis work was supported by the Portuguese Foundation for Science and Technology through the projects PTDC/EME-PME/098037/2008 and Pest-OE/EME/UI4044/2011.
dc.identifier.citationPereira, R.F., Bártolo, P.J. (2014). Photocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by Stereolithography. In: Fernandes, P., Bartolo, P. (eds) Tissue Engineering. Computational Methods in Applied Sciences, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7073-7_8.
dc.identifier.doi10.1007/978-94-007-7073-7_8
dc.identifier.isbn9789400770720
dc.identifier.isbn9789400770737
dc.identifier.issn1871-3033
dc.identifier.urihttp://hdl.handle.net/10400.8/13473
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Nature
dc.relationMultimaterial microstereo-thermal-lithography (μSTLG)
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://link.springer.com/chapter/10.1007/978-94-007-7073-7_8
dc.relation.ispartofComputational Methods in Applied Sciences
dc.relation.ispartofTissue Engineering
dc.rights.uriN/A
dc.subjectStereolithography
dc.subjectTissue engineering
dc.subjectbiomaterials
dc.subjectfabrication
dc.subjectphotocrosslinkable materials
dc.subjecttissue regeneration
dc.titlePhotocrosslinkable Materials for the Fabrication of Tissue-Engineered Constructs by Stereolithographyeng
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleMultimaterial microstereo-thermal-lithography (μSTLG)
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIhttp://hdl.handle.net/10400.8/13471
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.titleComputational Methods in Applied Sciences
oaire.fundingStream5876-PPCDTI
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_ab4af688f83e57aa
person.familyNameBrás Pereira
person.familyNameBartolo
person.givenNameRúben Filipe
person.givenNamePaulo
person.identifier1337969
person.identifier203086
person.identifier.ciencia-id9417-153E-4473
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-7255-3400
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridP-8503-2018
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55421048100
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
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Stereolithography is an additive technique that produces three-dimensional (3D) solid objects using a multi-layer procedure through the selective photoinitiated curing reaction of a liquid photosensitive material. Stereolithographic processes have been widely employed in Tissue Engineering for the fabrication of temporary constructs, using natural and synthetic polymers, and polymer-ceramic composites. These processes allow the fabrication of complex structures with a high accuracy and precision at physiological temperatures, incorporating cells and growth factors without significant damage or denaturation. Despite recent advances on the development of novel biomaterials and biocompatible crosslinking agents, the main limitation of these techniques are the lack number of available photocrosslinkable materials, exhibiting appropriate biocompatibility and biodegradability. This chapter gives an overview of the current state-of-art of materials and stereolithographic techniques to produce constructs for tissue regeneration, outlining challenges for future research.
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