Marine Natural Products as Anticancer Agents

Alves, Celso; Diederich, Marc

http://hdl.handle.net/10400.8/15671

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Marine natural products as anticancer agents.pdf	Cancer remains one of the major threats to human health and one of the deadliest diseases worldwide [1]. Therapy failure and consequent cancer relapse are the main factors contributing to high cancer mortality, making it crucial to find and develop new therapeutic options. Over the last few decades, natural products became one of the key drivers in the drug development of innovative cancer treatments [2]. In opposition to drug development from terrestrial resources, the marine environment only recently emerged as a prolific source of unparalleled structurally active metabolites [3]. Due to their excellent scaffold diversity, structural complexity, and ability to act on multiple cell signaling networks involved in carcinogenesis, marine natural products are ideal candidates to inspire the development of novel anticancer medicines [4,5].	199.77 KB	Adobe PDF	Ver/Abrir

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Autores

Alves, Celso

Diederich, Marc

Resumo(s)

Cancer remains one of the major threats to human health and one of the deadliest diseases worldwide [1]. Therapy failure and consequent cancer relapse are the main factors contributing to high cancer mortality, making it crucial to find and develop new therapeutic options. Over the last few decades, natural products became one of the key drivers in the drug development of innovative cancer treatments [2]. In opposition to drug development from terrestrial resources, the marine environment only recently emerged as a prolific source of unparalleled structurally active metabolites [3]. Due to their excellent scaffold diversity, structural complexity, and ability to act on multiple cell signaling networks involved in carcinogenesis, marine natural products are ideal candidates to inspire the development of novel anticancer medicines [4,5].