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Marine Natural Products as Anticancer Agents

datacite.subject.fosCiências Médicas::Outras Ciências Médicas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
datacite.subject.sdg15:Proteger a Vida Terrestre
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorAlves, Celso
dc.contributor.authorDiederich, Marc
dc.date.accessioned2026-02-18T15:16:36Z
dc.date.available2026-02-18T15:16:36Z
dc.date.issued2021-08-04
dc.description.abstractCancer remains one of the major threats to human health and one of the deadliest diseases worldwide [1]. Therapy failure and consequent cancer relapse are the main factors contributing to high cancer mortality, making it crucial to find and develop new therapeutic options. Over the last few decades, natural products became one of the key drivers in the drug development of innovative cancer treatments [2]. In opposition to drug development from terrestrial resources, the marine environment only recently emerged as a prolific source of unparalleled structurally active metabolites [3]. Due to their excellent scaffold diversity, structural complexity, and ability to act on multiple cell signaling networks involved in carcinogenesis, marine natural products are ideal candidates to inspire the development of novel anticancer medicines [4,5].eng
dc.description.sponsorshipFunding M.D. was supported by the National Research Foundation (NRF) (grant number 019R1A2C1009231). Support from Brain Korea (BK21) FOUR and the Creative-Pioneering Researchers Program at Seoul National University (funding number: 370C-20160062) are acknowledged. M.D. also acknowledges support by the “Recherche Cancer et Sang” Foundation (Luxembourg), “Recherches Scientifiques Luxembourg” (Luxembourg), “Een Häerz fir kriibskrank Kanner” (Luxembourg), Action Lions “Vaincre le Cancer” (Luxembourg), and Télévie Luxembourg. C.A. acknowledges the support by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UIDB/04292/2020 and UIDP/04292/2020 granted to MARE—Marine and Environmental Sciences Centre and through the CROSS-ATLANTIC project (PTDC/BIA-OUT/29250/2017). Acknowledgments As guest editors, we would like to sincerely acknowledge the efforts provided by all authors that participated in this Special Issue with their scientific outputs, all reviewers that carefully reviewed the manuscripts, the editorial board, and the Marine Drugs editorial office for their support and assistance, with special thanks to Grace Qu.
dc.identifier.citationAlves, C.; Diederich, M. Marine Natural Products as Anticancer Agents. Mar. Drugs 2021, 19, 447. https://doi.org/10.3390/md19080447.
dc.identifier.doi10.3390/md19080447
dc.identifier.eissn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.8/15671
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationMarine and Environmental Sciences Centre
dc.relationMarine and Environmental Sciences Centre
dc.relationPTDC/BIA-OUT/29250/2017
dc.relation.hasversionhttps://www.mdpi.com/1660-3397/19/8/447
dc.relation.ispartofMarine Drugs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMarine Natural Products
dc.subjectAnticancer Agents
dc.subjecthuman health
dc.subjectdeadliest diseases
dc.subjectcancer treatments
dc.subjectanticancer medicines
dc.titleMarine Natural Products as Anticancer Agentseng
dc.typeeditorial
dspace.entity.typePublication
oaire.awardTitleMarine and Environmental Sciences Centre
oaire.awardTitleMarine and Environmental Sciences Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04292%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04292%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBIA-OUT%2F29250%2F2017/PT
oaire.citation.endPage3
oaire.citation.issue8
oaire.citation.startPage1
oaire.citation.titleMarine Drugs
oaire.citation.volume19
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream9471 - RIDTI
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAlves
person.givenNameCelso
person.identifier159091
person.identifier.ciencia-id501C-F268-2E60
person.identifier.orcid0000-0003-1581-2127
person.identifier.scopus-author-id55654969100
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
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Cancer remains one of the major threats to human health and one of the deadliest diseases worldwide [1]. Therapy failure and consequent cancer relapse are the main factors contributing to high cancer mortality, making it crucial to find and develop new therapeutic options. Over the last few decades, natural products became one of the key drivers in the drug development of innovative cancer treatments [2]. In opposition to drug development from terrestrial resources, the marine environment only recently emerged as a prolific source of unparalleled structurally active metabolites [3]. Due to their excellent scaffold diversity, structural complexity, and ability to act on multiple cell signaling networks involved in carcinogenesis, marine natural products are ideal candidates to inspire the development of novel anticancer medicines [4,5].
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