CDRsp - Comunicações em conferências internacionais
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Percorrer CDRsp - Comunicações em conferências internacionais por Objetivos de Desenvolvimento Sustentável (ODS) "09:Indústria, Inovação e Infraestruturas"
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- Alginate/Aloe Vera Hydrogel Films for Biomedical ApplicationsPublication . Pereira, Rúben F.; Mendes, Ausenda; Bártolo, PauloThis paper describes a methodology to produce hydrogel films, composed of alginate and Aloe vera, for wound healing and drug delivery applications. The films were prepared through the solvent-casting method and subsequently submitted to an additional cross-linking step to improve their properties. Alginate films with different Aloe vera contents (5, 15 and 25%) were prepared and its properties evaluated in terms of thickness, transparency, swelling behavior and in vitro degradation. Results show a positive influence of Aloe vera on the transparency of the films, in both dry and wet state. Films were immersed in acetate buffer at pH 5.5 simulating the value of the skin, to evaluate its water absorption capacity. It was found that water absorption increases as the Aloe vera content increases, suggesting that Aloe vera enhances the hydrophilic properties of the films. The in vitro degradation tests were performed through the incubation of the films, for 10 weeks, in a simulated body fluid at 37°C. After this period, films kept its structure integrity exhibiting a weight loss in the range of 14.1-18.6%.
- Ask not what additive manufacturing can do for youPublication . Gibson, I.The paraphrase of John F Kennedy’s famous words is for 2 purposes. Firstly it is to acknowledge that there are some people who have considered that it is a major part of their life’s work to promote Additive Manufacturing (AM) technology as primarily a selfless act. AM comprises an outstanding range of technology that should be brought to public attention as a true revolution in how we design and manufacture products. The second purpose is to show that technology development is only one part of this promotion process and that there are other ways in which we can get involved. This paper describes the author’s journey over the (approximately) 20 years since he was introduced to what was then called Rapid Prototyping (RP). It is not a catalogue of research and development projects but rather a list of activities that he has been involved in to help promote and support AM technology over these years. It will describe the conferences, activities, associations and publications that have been created to allow academics and professionals to describe and discuss their work amongst themselves and to the larger society.
- Characterisation of PCL and PCL/PLA Scaffolds for Tissue EngineeringPublication . Patrício, T.; Domingos, M.; A. Gloria; Bártolo, P.This paper investigates the use of PCL and PCL/PLA scaffolds produced using a novel additive biomanufacturing system called BioCell Printing. PCL/PLA blends were prepared using melt blend and solvent casting techniques. Scaffolds with 0/90° architecture and 350 μm of pore size were morphologically evaluated using scanning electron microscopy and atomic force microscopy. Biological tests, using osteosarcoma cell line G-63, were performed using the Alamar Blue Assay and Alkaline Phosphatase Activity. Results show that the BioCell Printing system produces scaffolds with regular and reproducible architecture, presenting no toxicity and enhancing cell attachment and proliferation. It was also possible to observe that the addition of PLA to PCL scaffolds strongly improves the biomechanical performance of the constructs.
- Comparison by computer fluid dynamics of the drag force acting upon two helmets for wheelchair racersPublication . Forte, P; Marinho, D. A.; Morouço, P; Pascoal-Faria, P.; Barbosa, T. M.The aim of this study was to compare the drag force created by two helmets (time trial and road)used by a wheelchair racer. The head and helmet of the racer were scanned to obtain the3D models. Numerical simulation was run on Fluent, having as output the drag force for both helmets (road and time trial) in two different positions (0º and 90º) and increasing velocities (from 2.0 to 6.5 m/s). The greatest aerodynamic drag was noted wearing a time trial helmet in 90º ranging from 0.1025N to 0.8475N; this was also the position with the highest drag. The velocity with higher drag for booth helmets was at 6.5 m/s. The time trial helmet at 0º had the lower aerodynamic drag, compared with the same position of road helmet. The drag force seems to be lower wearing the time trial helmet and keeping the 0º position and, thus, should be considered for sprinting events.
- Computational technologies in tissue engineeringPublication . Almeida, H. A.; Bártolo, P. J.In last decades, many advances have been made in order to aid the medical community. Numerous computational technologies have been developed and improved the efficiency in diagnostic and treatment of many diseases. Many of the technologies were developed with the main goal of aiding in the research of genetic and viral diseases. Tissue engineering is a multidisciplinary field that requires the combined effort of cell biologists, engineers, material scientists, mathematicians, geneticists, and clinicians toward the development of biological substitutes that restore, maintain, or improve tissue function. The success of this emerging medical domain relies on the current technological advances. This paper presents an overview of the existing computational technologies that have been implemented in tissue engineering and the design of scaffolds for tissue engineering applications. These computational technologies contemplate medical imaging processing, numerical calculations (structural, vascular and topological) and biofabrication techniques necessary for the scaffolds optimum design and production.
- Cranial Biomechanical SimulationPublication . Perestrelo, Pedro; Bártolo, Paulo; Paranhos, Maurício; Noritomi, Pedro; Silva, JorgeIn order to improve the understanding, detection and prevention of traumatic brain injury (TBI), a step forward must be taken in the research. A pursue of biomechanical and clinical theories in separate, must give place to a joined effort. Therefore, it is proposed the development of a virtual platform using BioCAD protocol, surface modeling software and finite element method (FEM) analysis software, in order to achieve a model that can be adapted to the needs of the user or patient. This will result in an innovative and most needed tool, so that research and prevention of TBI enter a new level.
- Cyclic plastic behaviour of 7075 aluminium alloyPublication . Nogueira, F.; Cunha, J.; Mateus, A.; Malça, C.; Costa, J. D.; Branco, R.This paper aims at studying the cyclic plastic behaviour of the 7075-T651 aluminium alloy under fully-reversed strain-controlled conditions. Tests are conducted under strain-control mode, at room temperature, in a conventional servo-hydraulic machine, from smooth samples, using the single step method, with strain amplitudes (∆ε/2) in the range ±0.5 to ±2.75%. This material has exhibited a mixed behaviour, i.e. cyclic strain-hardens at higher strain amplitudes (∆ε/2/>1.1%) and cyclic strain-softens at lower strain amplitudes (∆ε/2<1.1%). A linear relationship between the degree of cyclic strain-hardening and the strain amplitude has been established for higher strain amplitudes. Fatigue-ductility and fatigue-strength properties agree with those found in the open literature for the same loading conditions.
- Degradation Behavior of Biopolymer-based Membranes for Skin Tissue RegenerationPublication . Pereira, Rúben F.; Bártolo, Paulo J.This research work investigates the long term in vitro degradation behavior of alginate-aloe vera composite membranes for skin regeneration. The membranes were prepared through a two-step procedure, which involves the synthesis of thin membranes and the crosslinking reaction. Degradation tests were performed through the immersion of the membranes into simulated body fluid solution at pH 7.4 and physiological temperature, during 6 months. Alginate-aloe vera membranes are resistant to the hydrolytic degradation and exhibit weight loss values in a range of 20.37-26.32%. Results show that an increase in the aloe vera content leads to a slight increase in the weight loss during the degradation process. Preliminary drug release studies, using nitrofurazone as a model drug, suggest the ability of the developed membranes to be used as a drug delivery system.
- A finite element method to study multimaterial wind towersPublication . Pascoal-Faria, P.; Dias, C.; Oliveira, M; Alves, N.Wind towers are used to produce electrical energy from the wind. A significant number of towers is manufactured using tubular separately steel or concrete, having limitations such as maximum diameter and height imposed essentially by transportation limitations. Developed computational studies on structural design of towers have been mainly focused on a single material. This investigation aims to develop a finite element method able to study structural design of wind towers combining different materials. The finite element model combines solid and shell elements encompassing different geometries. Several case studies are considered to validate the proposed method and accurate results are obtained.
- Further remarks on the "Smith is Huq" conditionPublication . Martins-Ferreira, Nelson; Van der Linden, TimWe compare the Smith is Huq condition (SH) with three commutator conditions in semi-abelian categories: first an apparently weaker condition which arose in joint work with Bourn and turns out to be equivalent with (SH), then an apparently equivalent condition which takes commutation of non-normal subobjects into account and turns out to be stronger than (SH). This leads to the even stronger condition that weighted commutators in the sense of Gran, Janelidze and Ursini are independent of the chosen weight, which is known to be false for groups but turns out to be true in any two-nilpotent semi-abelian category.