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ESSLei - Artigos em revistas nacionais

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http://hdl.handle.net/10400.8/5577

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Browsing ESSLei - Artigos em revistas nacionais by contributor "Oliveira, Mário"

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  • Antithrombotic therapy after stent implantation. One size does not fit all
    Publication . Morais, João; Oliveira, Mário
    The study published by Baptista et al.1 sought to assess the quality of antithrombotic therapy in a group of 996 patients with diabetes prior to coronary percutaneous intervention, searching for how guidelines are being applied in a realworld setting.
    2025-08Journal editorial Open access Show more
  • Sex-related differences in ST-segment elevation myocardial infarction: A Portuguese multicenter national registry analysis
    Publication . Gonçalves, Carolina Miguel; Carvalho, Mariana; Vazão, Adriana; Cabral, Margarida; Martins, André; Saraiva, Fátima; Morais, João; Oliveira, Mário
    Introduction and objectives Sex differences among patients with acute myocardial infarctions remain a matter of debate. Inequalities in presentation, diagnosis, treatment, and prognosis are frequently observed, contributing to a worse prognosis in women. The aim of this study was to investigate sex-related differences in Portuguese ST-segment elevation myocardial infarction (STEMI) patients. Methods The authors conducted a retrospective analysis of STEMI patients included in the Portuguese Registry on Acute Coronary Syndromes, between October 2010 and 2022. The two co-primary endpoints were in-hospital and one-year mortality. Results A total of 14 470 STEMI patients were studied. Women were underrepresented with 3721 individuals (25.7%). They were significantly older (70 vs. 62 years, p<0.001), with higher prevalence of cardiovascular risk factors, and underwent less frequently coronary angiography (84.4% vs. 88.5%, p<0.001) and guideline-directed medical therapy (e.g., aspirin 92.5% vs. 95.4%, beta blockers 79.2% vs. 83%, p<0.001). Furthermore, they experienced more complications, such as congestive heart failure (23.4% vs. 14.6%), ischemic stroke (47% vs. 40%), and in-hospital mortality (8.5% vs. 4.1%) (p<0.001 for all comparisons). Similarly, they presented higher one-year mortality (11.5% vs. 6.3%, p<0.001). However, after a multivariate analysis testing significant clinical variables, female sex remained an independent predictor for in-hospital (odds ratio=1.633; 95% CI [1.065–2.504]; p=0.025), but not for one-year mortality. Conclusions This analysis reveals sex-related disparities in Portuguese STEMI patients. Despite limitations inherent to registry-based analysis, women were significantly older, with increased cardiovascular risk, less treated, and with higher in-hospital mortality. These disparities should be a concern for clinicians to further improve outcomes and move toward equitable medical care.
    2025-03Journal article Open access Show more