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Tailoring Bioengineered Scaffolds for Regenerative Medicine

dc.contributor.authorAmado, Sandra
dc.contributor.authorMorouço, Pedro
dc.contributor.authorPascoal-Faria, Paula
dc.contributor.authorAlves, Nuno
dc.date.accessioned2023-05-31T13:15:57Z
dc.date.available2023-05-31T13:15:57Z
dc.date.issued2018
dc.description.abstractThe vision to unravel and develop biological healing mechanisms based on evolving molecular and cellular technologies has led to a worldwide scientific endeavor to establish regenerative medicine. This is a multidisciplinary field that involves basic and preclinical research and development on the repair, replacement, and regrowth or regeneration of cells, tissues, or organs in both diseases (congenital or acquired) and traumas. A total of over 63,000 patients were officially placed on organs’ waiting lists on 31 December 2013 in the European Union (European Commission, 2014). Tissue engineering and regen erative medicine have emerged as promising fields to achieve proper solutions for these concerns. However, we are far from having patient-specific tissue engineering scaffolds that mimic the native tissue regarding both structure and function. The proposed chapter is a qualitative review over the biomaterials, processes, and scaffold designs for tailored bioprinting. Relevant literature on bioengineered scaffolds for regenerative medicine will be updated. It is well known that mechanical properties play significant effects on bio logic behavior which highlight the importance of an extensively discussion on tailoring biomechanical properties for bioengineered scaffolds. The following topics will be dis cussed: scaffold design, biomaterials and scaffolds bioactivity, biofabrication processes, scaffolds biodegradability, and cell viability. Moreover, new insights will be pointed out.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.5772/intechopen.69857pt_PT
dc.identifier.isbn978-953-51-3777-1
dc.identifier.urihttp://hdl.handle.net/10400.8/8545
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIntechOpenpt_PT
dc.relation.publisherversionhttps://www.intechopen.com/chapters/56531pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectRegenerative medicinept_PT
dc.subjectBiomechanicspt_PT
dc.subjectBioprintingpt_PT
dc.subjectBiomaterialspt_PT
dc.subjectTailored scaffoldpt_PT
dc.titleTailoring Bioengineered Scaffolds for Regenerative Medicinept_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.endPage360pt_PT
oaire.citation.startPage341pt_PT
oaire.citation.titleBiomaterials in Regenerative Medicinept_PT
person.familyNameAmado
person.familyNameMorouço
person.familyNamePascoal-Faria
person.familyNameAlves
person.givenNameSandra
person.givenNamePedro
person.givenNamePaula
person.givenNameNuno
person.identifier804352
person.identifier435983
person.identifier452149
person.identifier.ciencia-idD617-149A-8102
person.identifier.ciencia-idF619-3996-742A
person.identifier.ciencia-idE01D-874A-4145
person.identifier.ciencia-id311E-1559-8F6C
person.identifier.orcid0000-0001-8356-4810
person.identifier.orcid0000-0002-5956-9790
person.identifier.orcid0000-0003-1474-9496
person.identifier.orcid0000-0002-5016-0868
person.identifier.ridO-6988-2016
person.identifier.ridK-9545-2013
person.identifier.ridN-4073-2013
person.identifier.scopus-author-id16038616600
person.identifier.scopus-author-id24339135400
person.identifier.scopus-author-id7006403383
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT
relation.isAuthorOfPublicationaea9bcf4-4f9f-4b2d-9d73-fec5ad76dcc4
relation.isAuthorOfPublication05b28d80-9e18-41cc-a66c-f37955bfc8da
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relation.isAuthorOfPublication.latestForDiscovery05b28d80-9e18-41cc-a66c-f37955bfc8da

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