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Advisor(s)
Abstract(s)
The vision to unravel and develop biological healing mechanisms based on evolving
molecular and cellular technologies has led to a worldwide scientific endeavor to establish
regenerative medicine. This is a multidisciplinary field that involves basic and preclinical
research and development on the repair, replacement, and regrowth or regeneration of
cells, tissues, or organs in both diseases (congenital or acquired) and traumas. A total of
over 63,000 patients were officially placed on organs’ waiting lists on 31 December 2013
in the European Union (European Commission, 2014). Tissue engineering and regen erative medicine have emerged as promising fields to achieve proper solutions for these
concerns. However, we are far from having patient-specific tissue engineering scaffolds
that mimic the native tissue regarding both structure and function. The proposed chapter
is a qualitative review over the biomaterials, processes, and scaffold designs for tailored
bioprinting. Relevant literature on bioengineered scaffolds for regenerative medicine will
be updated. It is well known that mechanical properties play significant effects on bio logic behavior which highlight the importance of an extensively discussion on tailoring
biomechanical properties for bioengineered scaffolds. The following topics will be dis cussed: scaffold design, biomaterials and scaffolds bioactivity, biofabrication processes,
scaffolds biodegradability, and cell viability. Moreover, new insights will be pointed out.
Description
Keywords
Regenerative medicine Biomechanics Bioprinting Biomaterials Tailored scaffold
Citation
Publisher
IntechOpen