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Comprehensive review on full bone regeneration through 3D printing approaches

dc.contributor.authorFernandes, Cristiana
dc.contributor.authorMoura, Carla
dc.contributor.authorAscenso, Rita M.T.
dc.contributor.authorAmado, Sandra
dc.contributor.authorAlves, Nuno
dc.contributor.authorPascoal-Faria, Paula
dc.date.accessioned2023-04-21T10:18:53Z
dc.date.available2023-04-21T10:18:53Z
dc.date.issued2020
dc.descriptionThis work is supported by the Fundação para a Ciência e Tecnologia (FCT) and Centro2020 through the Project references UID/Multi/04044/2019, PAMI—ROTEIRO/0328/2013 (NO. 022158), and MATIS (CENTRO-01-0145-FEDER-000014-3362). It is also funded by the projects insitu.Biomas (POCI-01-0247-FEDER-017771), Bone2Move (PTDC/CVT-CVT/31146/2017), and Stimuli2BioScaffolds (PTDC/EME-SIS/32554/2017).pt_PT
dc.description.abstractOver the last decades, the number of work accidents associated with bone fractures has increased leading to a growing concern worldwide. Currently, autografts, allografts, and xenografts are used for bone regeneration. However, their application has associated risks. Tissue engineering (TE) has brought solutions to address these problems, through the production of temporary supports, providing mechanical support to the formation of new bone tissue and biocompatible and biodegradable scaffolds, which allow cell adhesion and proliferation to ensure bone formation. The combination of materials and structure with the technique to be used will directly influence their physical and chemical properties and, consequently, their action in contributing to bone regeneration. Thus, the focus of this chapter is to perform an exhaustive literature review and a critical analysis of the state of the art in bone TE and present a proposal of an optimized temporary support geometry for bone regeneration in case of large bone defects. For this, it was listed and identified the best choice of biomaterials, fabrication method, cell type and their culture conditions (static vs. dynamic), and/or the inclusion of growth factors for the repair of large bone defects.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFernandes, C., Ascenso, R., Moura, C., Amado, S., Alves, N. & Pascoal-Faria, P. (2020). Comprehensive Review on Full Bone Regeneration through 3D Printing Approaches. In E. Yasa, M. Mhadhbi & E. Santecchia, Design and manufacturing (chapter 10). IntechOpen. 10.5772/intechopen.90864.pt_PT
dc.identifier.doi10.5772/intechopen.90864pt_PT
dc.identifier.issn978-1-78985-866-2
dc.identifier.urihttp://hdl.handle.net/10400.8/8431
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIntechOpenpt_PT
dc.relationCentre for Rapid and Sustainable Product Development
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectLarge bone defectspt_PT
dc.subjectBone regenerationpt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectCell culturept_PT
dc.subjectCADpt_PT
dc.subjectScaffoldspt_PT
dc.subjectAdditive manufacturingpt_PT
dc.titleComprehensive review on full bone regeneration through 3D printing approachespt_PT
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleCentre for Rapid and Sustainable Product Development
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FEME-SIS%2F32554%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FCVT-CVT%2F31146%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F04044%2F2019/PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStream9471 - RIDTI
oaire.fundingStream6817 - DCRRNI ID
person.familyNameFernandes
person.familyNameMonteiro de Moura
person.familyNameTeixeira Ascenso
person.familyNameAmado
person.familyNameAlves
person.familyNamePascoal-Faria
person.givenNameCristiana Henriques
person.givenNameCarla Sofia
person.givenNameRita Margarida
person.givenNameSandra
person.givenNameNuno
person.givenNamePaula
person.identifier804352
person.identifier452149
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person.identifier.ciencia-id5D1F-04DB-7430
person.identifier.ciencia-idD617-149A-8102
person.identifier.ciencia-id311E-1559-8F6C
person.identifier.ciencia-idE01D-874A-4145
person.identifier.orcid0000-0001-6371-800X
person.identifier.orcid0000-0003-2610-1005
person.identifier.orcid0000-0001-8011-2333
person.identifier.orcid0000-0001-8356-4810
person.identifier.orcid0000-0002-5016-0868
person.identifier.orcid0000-0003-1474-9496
person.identifier.ridD-7775-2016
person.identifier.ridO-6988-2016
person.identifier.ridN-4073-2013
person.identifier.scopus-author-id28067490200
person.identifier.scopus-author-id16038616600
person.identifier.scopus-author-id7006403383
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT
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