Repository logo
 
Publication

Red seaweed-derived compounds as a potential new approach for acne vulgaris care

2021Journal article Open access
Simple item page
dc.contributor.authorJanuário, Adriana P.
dc.contributor.authorFélix, Rafael
dc.contributor.authorFélix, Carina
dc.contributor.authorReboleira, João
dc.contributor.authorValentão, Patrícia
dc.contributor.authorLemos, Marco F.L.
dc.date.accessioned2022-08-17T08:02:01Z
dc.date.available2022-08-17T08:02:01Z
dc.date.issued2021
dc.descriptionFunding: This study had the support of the Fundação para a Ciência e a Tecnologia (FCT) Strategic Projects UID/MAR/04292/2020 and UIDB/50006/2020 granted to MARE and REQUIMTE, respectively; the grant awarded to A.P.J. (2020.08202.BD); and project MARINE INVADERS (POCI-01-0145-FEDER-031144). The authors also wish to acknowledge the support of the European Union through EASME Blue Labs project AMALIA, Algae-to-MArket Lab IdeAs (EASME/EMFF/2016/1.2.1.4/03/SI2.750419). The project was also partially funded by RDandT co-promotion project ORCHESTRA (POCI-01-0247-FEDER-070155) through COMPETE, Portugal 2020 and FCT, and COSMOS (MAR-04.03.01-FEAMP-0370) through GAL PESCA OESTE and MAR2020 in the framework of PORTUGAL2020 and the European Maritime and Fisheries Fund.pt_PT
dc.description.abstractAcne vulgaris (AV) is a chronic skin disease of the pilosebaceous unit affecting both adolescents and adults. Its pathophysiology includes processes of inflammation, increased keratinization, sebum production, hormonal dysregulation, and bacterial Cutibacterium acnes proliferation. Common AV has been treated with antibiotics since the 1960s, but strain resistance has emerged and is of paramount concern. Macroalgae are known producers of substances with bioactive properties, including anti-viral, antibacterial, antioxidant, and anti-inflammatory properties, among several others. In particular, red algae are rich in bioactive compounds such as polysaccharides, phenolic compounds, lipids, sterols, alkaloids, and terpenoids, conferring them antioxidant, antimicrobial, and anti-inflammatory activities, among others. Thus, the exploration of compounds from marine resources can be an appealing approach to discover new treatment options against AV. The aim of this work is to provide an overview of the current knowledge of the potentialities of red macroalgae in the treatment of AV by reviewing the main therapeutic targets of this disease, and then the existence of compounds or extracts with bioactive properties against them.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJanuário, A.P.; Félix, R.; Félix, C.; Reboleira, J.; Valentão, P.; Lemos, M.F.L. Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care. Pharmaceutics 2021, 13, 1930. https://doi.org/10.3390/pharmaceutics13111930pt_PT
dc.identifier.doi10.3390/pharmaceutics13111930pt_PT
dc.identifier.issn1999-4923
dc.identifier.urihttp://hdl.handle.net/10400.8/7542
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationUID/MAR/04292/2020pt_PT
dc.relationAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
dc.relationMitoBONE - Orchestrating Osteoclast Differentiation Through ROS and Mitochondrial Regulation
dc.relation.publisherversionhttps://www.mdpi.com/1999-4923/13/11/1930pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAcne pathophysiologypt_PT
dc.subjectAntibacterialpt_PT
dc.subjectBioactive compoundspt_PT
dc.subjectCutibacterium acnespt_PT
dc.subjectInflammationpt_PT
dc.subjectRhodophytapt_PT
dc.subjectSeaweed extractspt_PT
dc.titleRed seaweed-derived compounds as a potential new approach for acne vulgaris carept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
oaire.awardTitleMitoBONE - Orchestrating Osteoclast Differentiation Through ROS and Mitochondrial Regulation
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/Investigador FCT/IF%2F01182%2F2015%2FCP1280%2FCT0007/PT
oaire.citation.endPage32pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titlePharmaceuticspt_PT
oaire.citation.volume13pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamInvestigador FCT
person.familyNameJanuário
person.familyNameFaria da Costa Félix
person.familyNameFaria Da Costa Félix
person.familyNameMendes Reboleira
person.familyNameRibeiro Valentão
person.familyNameLemos
person.givenNameAdriana P.
person.givenNameRafael Alexandre
person.givenNameCarina Rafaela
person.givenNameJoão
person.givenNamePatrícia Carla
person.givenNameMarco
person.identifierKWTr8tQAAAAJ
person.identifier996337
person.identifier.ciencia-id241B-FEA3-3BED
person.identifier.ciencia-idA315-5CB0-097C
person.identifier.ciencia-id2015-2A43-2055
person.identifier.ciencia-idA014-8343-2B4E
person.identifier.ciencia-idCF15-A295-BC33
person.identifier.orcid0000-0002-3228-922X
person.identifier.orcid0000-0003-4766-3736
person.identifier.orcid0000-0002-9813-9400
person.identifier.orcid0000-0003-3261-6857
person.identifier.orcid0000-0002-0740-4396
person.identifier.orcid0000-0001-9887-1864
person.identifier.ridF-7951-2011
person.identifier.scopus-author-id57200377641
person.identifier.scopus-author-id7006042884
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication576c1b04-ad90-4771-80f0-e42f080e3b2b
relation.isAuthorOfPublicationd4d70589-8897-4538-b004-bfe2ce623b69
relation.isAuthorOfPublicationbe3b35be-8af5-4b3b-aaf3-12d6cf143985
relation.isAuthorOfPublicationbe4114d5-4394-45ce-87bb-7724cfefb23f
relation.isAuthorOfPublicationb0dccc48-82e4-4ec6-965f-774e8f177d2d
relation.isAuthorOfPublicationf21e5540-df76-43e9-ad64-93edd70da1f1
relation.isAuthorOfPublication.latestForDiscoverybe3b35be-8af5-4b3b-aaf3-12d6cf143985
relation.isProjectOfPublication49eb7a0c-4c73-4544-8b3d-cb4cf75e403c
relation.isProjectOfPublication60abd678-6023-41cb-b528-bad1bb49e8b8
relation.isProjectOfPublication.latestForDiscovery49eb7a0c-4c73-4544-8b3d-cb4cf75e403c

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Januario et al_2021_Pharmaceutics.pdf
Size:
919.68 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.32 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

MARE - Artigos com peer review
ESTM - Artigos em revistas internacionais