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CBmeter study: Protocol for assessing the predictive value of peripheral chemoreceptor overactivation for metabolic diseases

2021Journal article Open access
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dc.contributor.authorLages, Marlene
dc.contributor.authorCarvalho, Lucinda
dc.contributor.authorFeijó, Salvato
dc.contributor.authorVieira, Alexandra
dc.contributor.authorFonseca-Pinto, Rui
dc.contributor.authorGuarino, Maria Pedro
dc.date.accessioned2022-05-13T09:11:08Z
dc.date.available2022-05-13T09:11:08Z
dc.date.issued2021
dc.description.abstractEarly screening of metabolic diseases is crucial since continued undiagnostic places an ever-increasing burden on healthcare systems. Recent studies suggest a link between overactivated carotid bodies (CB) and the genesis of type 2 diabetes mellitus. The non-invasive assessment of CB activity by measuring ventilatory, cardiac and metabolic responses to challenge tests may have predictive value for metabolic diseases; however, there are no commercially available devices that assess CB activity. The findings of the CBmeter study will clarify the role of the CBs in the genesis of—metabolic diseases and guide the development of new therapeutic approaches for early intervention in metabolic disturbances. Results may also contribute to patient classification and stratification for future CB modulatory interventions.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLages M, Carvalho L, Feijó S, et al. CBmeter study: protocol for assessing the predictive value of peripheral chemoreceptor overactivation for metabolic diseases. BMJ Open 2021;11:e042825. doi:10.1136/ bmjopen-2020-042825pt_PT
dc.identifier.doi10.1136/bmjopen-2020-042825pt_PT
dc.identifier.eissn2044-6055
dc.identifier.urihttp://hdl.handle.net/10400.8/7128
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Publishing Grouppt_PT
dc.relation.ispartofseries8;
dc.relation.publisherversionhttps://bmjopen.bmj.com/content/11/8/e042825pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.titleCBmeter study: Protocol for assessing the predictive value of peripheral chemoreceptor overactivation for metabolic diseasespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagee042825pt_PT
oaire.citation.titleBMJ Openpt_PT
oaire.citation.volume11pt_PT
person.familyNameLages
person.familyNameCarvalho
person.familyNameFeijó
person.familyNameFonseca-Pinto
person.familyNameGuarino
person.givenNameMarlene
person.givenNameLucinda Sofia
person.givenNameSalvato
person.givenNameRui
person.givenNameMaria Pedro
person.identifier.ciencia-idC613-4639-10A8
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person.identifier.ciencia-idF21A-BD01-2D52
person.identifier.orcid0000-0002-7389-6368
person.identifier.orcid0000-0002-0549-4666
person.identifier.orcid0000-0002-8871-1370
person.identifier.orcid0000-0001-6774-5363
person.identifier.orcid0000-0001-6079-1105
person.identifier.ridK-9449-2014
person.identifier.ridB-5594-2015
person.identifier.scopus-author-id16241713300
person.identifier.scopus-author-id26039086400
person.identifier.scopus-author-id56348477000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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