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Development of novel alginate based hydrogel films for wound healing applications

dc.contributor.authorPereira, Rúben
dc.contributor.authorCarvalho, Anabela
dc.contributor.authorVaz, Daniela C.
dc.contributor.authorGil, M. H.
dc.contributor.authorMendes, Ausenda
dc.contributor.authorBártolo, Paulo
dc.date.accessioned2019-10-29T11:26:11Z
dc.date.available2019-10-29T11:26:11Z
dc.date.issued2013
dc.date.updated2019-10-28T11:34:57Z
dc.description.abstractAlginate and Aloe vera are natural materials widely investigated and used in the biomedical field. In this research work, thin hydrogel films composed by alginate and Aloe vera gel in different proportions (95:5, 85:15 and 75:25, v/v) were prepared and characterized. The films were evaluated regarding the light transmission behavior, contact angle measurements, and chemical, thermal and mechanical properties. These thin hydrogel films, prepared by crosslinking reaction using 5% calcium chloride solution, were also investigated relatively to their water solubility and swelling behavior. Results showed that Aloe vera improved the transparency of the films, as well their thermal stability. The developed films present adequate mechanical properties for skin applications, while the solubility studies demonstrated the insolubility of the films after 24 h of immersion in distilled water. The water absorption and swelling behavior of these films were greatly improved by the increase in Aloe vera proportion.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPereira R, Carvalho A, Vaz DC, Gil MH, Mendes A, Bártolo P. (2013) Development of novel alginate based hydrogel films for wound healing applications. Int J Biol Macromol. 2013 Jan; 52:221-30.pt_PT
dc.identifier.doi10.1016/j.ijbiomac.2012.09.031
dc.identifier.other2-s2.0-84869222321
dc.identifier.slugcv-prod-179870
dc.identifier.urihttp://hdl.handle.net/10400.8/4254
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.ispartofInternational Journal of Biological Macromoleculesen_US
dc.subjectAlginatept_PT
dc.subjectAloe verapt_PT
dc.subjectFilmpt_PT
dc.subjectHydrogelpt_PT
dc.subjectWound healingpt_PT
dc.titleDevelopment of novel alginate based hydrogel films for wound healing applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.endPage230pt_PT
oaire.citation.startPage221pt_PT
oaire.citation.titleInternational Journal of Biological Macromoleculespt_PT
oaire.citation.volume52pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameBrás Pereira
person.familyNameBarroso de Moura Cipreste Vaz
person.familyNameMendes
person.familyNameBartolo
person.givenNameRúben Filipe
person.givenNameDaniela
person.givenNameAusenda
person.givenNamePaulo
person.identifier1337969
person.identifier203086
person.identifier.ciencia-id9417-153E-4473
person.identifier.ciencia-id801A-7761-328C
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-7255-3400
person.identifier.orcid0000-0001-7562-4676
person.identifier.orcid0000-0003-3004-8972
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridP-8503-2018
person.identifier.ridR-5243-2017
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55421048100
person.identifier.scopus-author-id6602838931
person.identifier.scopus-author-id7102443940
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.cv.cienciaid801A-7761-328C | Daniela Maria Barroso de Moura Cipreste Vaz
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication518f12af-3297-4334-b00b-c06e17b2cf27
relation.isAuthorOfPublication5ac3b700-95c6-4782-861a-deea8e449a7c
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