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Sex Differences in Age-Related Functional Mobility Decline: A Moderated Mediation Analysis

2026-06-30Artigo de investigação Acesso aberto
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datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg04:Educação de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
dc.contributor.authorRodrigues, Filipe
dc.contributor.authorBastos, Vasco
dc.contributor.authorTeixeira, Diogo Santos
dc.contributor.authorMonteiro, Diogo
dc.date.accessioned2026-07-02T14:23:07Z
dc.date.available2026-07-02T14:23:07Z
dc.date.issued2026-06-30en_US
dc.date.updated2026-07-01T06:16:33Z
dc.description.abstractWhile functional mobility is known to deteriorate with age, the specific mechanisms driving this decline, along with potential differences between men and women, are not fully established. Therefore, the present study applied a moderated mediation framework to investigate whether lower limb strength and body mass index (BMI) mediate the relationship between aging and functional mobility, and to explore if sex acts as a moderator in these relationships. A cross-sectional design was used to evaluate 408 independent older adults (mean age: 71.9 ± 3.9 years; 273 females and 135 males). Assessments included the Timed Up and Go (TUG) for functional mobility, the 30 s Chair Stand for leg strength, alongside BMI calculations. Direct and indirect pathways were subsequently evaluated using a moderated mediation analysis. Lower limb strength and BMI significantly predicted functional mobility in both sexes (p < 0.05), with no significant moderation in the indirect pathways. Regarding conditional effects, advancing age predicted poorer functional mobility in females (p = 0.008) but not in males (p = 0.141), independent of the mediators. Strength and BMI appear to be correlates of functional mobility. However, since the age-by-sex interaction term was not statistically significant, the potential sex-specific direct effect of age must be interpreted with caution. While these findings hint at possible subtle differences in aging trajectories, future research is needed to confirm whether interventions for older women require addressing factors beyond strength and body composition.eng
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationRodrigues, F., Bastos, V., Teixeira, D. S., & Monteiro, D. (2026). Sex Differences in Age-Related Functional Mobility Decline: A Moderated Mediation Analysis. Sports, 14(7), 270. https://doi.org/10.3390/sports14070270
dc.identifier.doi10.3390/sports14070270en_US
dc.identifier.issn2075-4663en_US
dc.identifier.slugcv-prod-5062507
dc.identifier.urihttp://hdl.handle.net/10400.8/16517
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationResearch Center in Sports Sciences, Health Sciences and Human Development
dc.relation.hasversionhttps://www.mdpi.com/2075-4663/14/7/270
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectsarcopeniaen_US
dc.subjectfunctional mobilityen_US
dc.subjectagingen_US
dc.subjectsex characteristicsen_US
dc.subjectmuscle strengthen_US
dc.titleSex Differences in Age-Related Functional Mobility Decline: A Moderated Mediation Analysisen_US
dc.typeresearch articleen_US
dspace.entity.typePublication
oaire.awardNumberUID/DTP/04045/2019
oaire.awardTitleResearch Center in Sports Sciences, Health Sciences and Human Development
oaire.awardURIhttp://hdl.handle.net/10400.8/14238
oaire.citation.issue7en_US
oaire.citation.startPage270
oaire.citation.titleSportsen_US
oaire.citation.volume14en_US
oaire.fundingStreamFinanciamento do Plano Estratégico de Unidades de I&D - 2019
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameRodrigues
person.familyNameMonteiro
person.givenNameFilipe
person.givenNameDiogo
person.identifier613329
person.identifierF-1202-2015
person.identifier.ciencia-id9B18-7FE1-74AF
person.identifier.ciencia-idED1F-6228-E26F
person.identifier.orcid0000-0003-1327-8872
person.identifier.orcid0000-0002-7179-6814
person.identifier.ridA-8152-2019
person.identifier.scopus-author-id57206270107
person.identifier.scopus-author-id56437945500
rcaap.cv.cienciaidED1F-6228-E26F | Diogo Manuel Teixeira Monteiro
rcaap.rightsopenAccessen_US
relation.isAuthorOfPublication661e2126-79f7-445a-bda0-eb4c9d0bb0e2
relation.isAuthorOfPublication79dcae83-d54a-4acc-a9a1-8268c7776ab9
relation.isAuthorOfPublication.latestForDiscovery661e2126-79f7-445a-bda0-eb4c9d0bb0e2
relation.isProjectOfPublication0d7d01bd-1227-427b-a242-17cfca8677be
relation.isProjectOfPublication.latestForDiscovery0d7d01bd-1227-427b-a242-17cfca8677be

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