Percorrer por autor "Stollenwerk, N."
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- Dynamics and Biological ThresholdsPublication . Burroughs, N. J.; Ferreira, M.; Martins, J.; Oliveira, B. M. P. M.; Pinto, Alberto A.; Stollenwerk, N.Our main interest is to study the relevant biological thresholds that appear in epidemic and immunological dynamical models. We compute the thresholds, of the SIRI epidemic models, that determine the appearance of an epidemic disease. We compute the thresholds, of a Tregs immunological model, that determine the appearance of an immune response.
- Scaling of Stochasticity in Dengue Hemorrhagic Fever EpidemicsPublication . Aguiar, M.; Kooi, B.W.; Martins, J.; Stollenwerk, N.In this paper we analyze the stochastic version of a minimalistic multi-strain model, which captures essential differences between primary and secondary infections in dengue fever epidemiology, and investigate the interplay between stochasticity, seasonality and import. The introduction of stochasticity is needed to explain the fluctuations observed in some of the avail- able data sets, revealing a scenario where noise and complex deterministic skeleton strongly interact. For large enough population size, the stochastic system can be well described by the deterministic skeleton gaining insight on the relevant parameter values purely on topological information of the dynamics, rather than classical parameter estimation of which application is in general restricted to fairly simple dynamical scenarios.