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Publicação
Obtención de andamios biodegradables mediante bioextrusión
Orientador(es)
Resumo(s)
En esta investigación se obtuvieron andamios biodegradables de mezclas de poli-(ácido láctico)/poli-(ε-caprolactona)
(PLA/PCL) obtenidas en solución, cuyas proporciones en peso/peso (p/p) fueron 100/0, 90/10, 80/20, 0/100, mediante la
técnica de biofabricación conocida como bioextrusión. Todas las mezclas fueron caracterizadas por Espectroscopía
Infrarroja por Transformada de Fourier (FT-IR) y Calorimetría Diferencial de Barrido (DSC), observándose la variación
en la morfología y la cristalinidad cuando el material se encontraba orientado (andamios) y sin orientar (mezclas iniciales).
Mediante Microscopía Electrónica de Barrido (MEB) se observó la distribución de orientación, porosidad e
interconectividad, características de un andamio biodegradable.
In this investigation biodegradable scaffolds were obtained from mixtures of poly-(lactic acid)/poly-(ε-caprolactone) (PLA/PCL) obtained in solution, whose proportions in weight/weight (w/w) were 100/0, 90/10, 80/20, 0/100, using the technique known as bioextrusion. All blends were characterized by Fourier Transform Infrared Spectroscopy (FT-IR) and Differential Scanning Calorimetry (DSC), showing the variation in the morphology and crystallinity when the material was oriented (scaffolds) and unoriented (original mixtures). By Scanning Electron Microscopy (SEM) the distribution of orientation, porosity and interconnectivity were observed, these are characteristics of a biodegradable scaffold.
In this investigation biodegradable scaffolds were obtained from mixtures of poly-(lactic acid)/poly-(ε-caprolactone) (PLA/PCL) obtained in solution, whose proportions in weight/weight (w/w) were 100/0, 90/10, 80/20, 0/100, using the technique known as bioextrusion. All blends were characterized by Fourier Transform Infrared Spectroscopy (FT-IR) and Differential Scanning Calorimetry (DSC), showing the variation in the morphology and crystallinity when the material was oriented (scaffolds) and unoriented (original mixtures). By Scanning Electron Microscopy (SEM) the distribution of orientation, porosity and interconnectivity were observed, these are characteristics of a biodegradable scaffold.
Descrição
Palavras-chave
Biodegradable scaffolds Bioextrusion Polyblends poly-(lactic acid)/poly-(ε-caprolactone) Andamios biodegradables bioextrusión polimezcla poli-(ácido láctico)/poli-(ε-caprolactona)
Contexto Educativo
Citação
Loaiza M.C., Sabino M.A., Bártolo P.J., Domingos M., Müller A.J., Obtaining biodegradable scaffolds through bioextrusion [Obtención de andamios biodegradables mediante bioextrusión] (2011) Revista Latinoamericana de Metalurgia y Materiales, (SUPPL. 3), pp. 22 - 23.
Editora
Universidad Simon Bolivar