A Novel Biomanufacturing System to Produce Multi-Material Scaffolds for Tissue Engineering: Concept and Preliminary Results

Viana, T.; Biscaia, S.; Dabrowska, E.; Franco, M.; Carreira, P.; Morouço, P.; Alves, N.

http://hdl.handle.net/10400.8/8149

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
6 -  A novel biomanufacturing system_AMM.890.283.pdf		1.28 MB	Adobe PDF	Download

Send Feedback

Authors

Abstract(s)

This research work aims to validate a new system that enables the fabrication of multimaterial 3D structures using poly(e-caprolactone) and sodium alginate for potential use in Tissue Engineering applications. To produce multi-material scaffolds for Tissue Engineering, accurate techniques are needed to obtain three-dimensional constructs with clinically appropriate size and structural integrity. This paper presents a novel biomanufacturing system which can fabricate 3D scaffolds with precise shape and porosity, through the control of all fabrication modules by an integrated computational platform. The incorporation of a clean flow unit and a camera makes it possible to produce scaffolds in a clean environment and provides a monitoring tool to analyse constructs during the production, respectively.

Keywords

Tissue engineering Biomanufacturing Bioprinting Micro-extrusion Heterogenous Scaffolds

URI

http://hdl.handle.net/10400.8/8149

Citation

Viana, T., Biscaia, S., Dabrowska, E., Franco, M. C., Carreira, P., Morouço, P., & Alves, N. (2019). A Novel Biomanufacturing System to Produce Multi-Material Scaffolds for Tissue Engineering: Concept and Preliminary Results. Applied Mechanics and Materials, 890, 283–289. https://doi.org/10.4028/www.scientific.net/amm.890.283