Natural polymers for bone repair

Rodríguez, GB Ramírez; Patrício, TMF; López, JM Delgado

Publication

Natural polymers for bone repair

2019Book part

dc.contributor.author	Rodríguez, GB Ramírez
dc.contributor.author	Patrício, TMF
dc.contributor.author	López, JM Delgado
dc.date.accessioned	2023-06-21T13:47:51Z
dc.date.available	2023-06-21T13:47:51Z
dc.date.issued	2019
dc.description.abstract	The substitution of tissues due to tumors, pathologies, or traumatic accidents is well known, and different surgical branches perform these kinds of surgeries on a daily basis with relative ease. The substitution of bone tissue is especially relevant as it contributes to the structural stability of the body. Bone tissue is composed of an organic matrix, a mineral component, and water in approximately similar volumes. The combination of these elements forms a composite material with different hierarchical levels in its microstructure. The reproduction of this highly hierarchical structure is still not possible. Historically, articular prostheses have been made of metallic materials due to the high mechanical tensions that they suffer once implanted, as well as good fatigue resistance and tenacity. Lately, the use of polymeric materials has attracted a great deal of attention. On the other hand, the choice of a material for the filling of bone defects or bone cavities is greater, ranging from biodegradable polymers to calcium phosphate cements and ceramics. The role of polymers in bone substitution is relevant but limited to a few applications, such as articulating bearing surfaces of joint replacements, both hip and knee, and as interpositional cementing material between the implant surface and the bone. In the first application, the ultimate choice is ultrahigh molecular weight polyethylene, and in the second application the most used polymer is poly(methyl methacrylate). The use of biodegradable polymers has grown significantly in applications dealing with support structures needed for normal movements of articulating joints. In this chapter, the most used polymers in orthopedic applications will be described. Special emphasis will be given to their physical and chemical properties.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	GB Ramírez Rodríguez, TMF Patrício, JM Delgado López, 8 - Natural polymers for bone repair, Editor(s): Kendell M. Pawelec, Josep A. Planell, In Woodhead Publishing Series in Biomaterials, Bone Repair Biomaterials (Second Edition), Woodhead Publishing, 2019, Pages 199-232, ISBN 9780081024515, https://doi.org/10.1016/B978-0-08-102451-5.00008-1	pt_PT
dc.identifier.doi	https://doi.org/10.1016/B978-0-08-102451-5.00008-1.	pt_PT
dc.identifier.isbn	9780081024515
dc.identifier.uri	http://hdl.handle.net/10400.8/8618
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Elsevier	pt_PT
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/abs/pii/B9780081024515000081	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Biomimetic mineralization	pt_PT
dc.subject	Bioprinting	pt_PT
dc.subject	Bone tissue engineering	pt_PT
dc.subject	Cell encapsulation	pt_PT
dc.subject	Collagen	pt_PT
dc.subject	Cross-linking	pt_PT
dc.subject	Growth factor	pt_PT
dc.subject	Natural polymer	pt_PT
dc.subject	Scaffold	pt_PT
dc.title	Natural polymers for bone repair	pt_PT
dc.type	book part
dspace.entity.type	Publication
oaire.citation.endPage	232	pt_PT
oaire.citation.startPage	199	pt_PT
oaire.citation.title	Bone Repair Biomaterials	pt_PT
oaire.citation.volume	8	pt_PT
person.familyName	Fernandes Patrício
person.givenName	Tatiana Marisa
person.identifier	L-2781-2015
person.identifier.ciencia-id	EF1C-430E-9F29
person.identifier.orcid	0000-0003-0672-9014
person.identifier.scopus-author-id	55749853300
rcaap.rights	openAccess	pt_PT
rcaap.type	bookPart	pt_PT
relation.isAuthorOfPublication	c256ec7c-9a07-42d9-84a2-6885b5392a00
relation.isAuthorOfPublication.latestForDiscovery	c256ec7c-9a07-42d9-84a2-6885b5392a00