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Self-Reported Post-COVID Symptoms at 18 Months After Infection Among Adults in Southern Brazil: A Cross-Sectional Study

2025-01-23Journal article Open access
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datacite.subject.fosCiências Médicas::Ciências da Saúde
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg17:Parcerias para a Implementação dos Objetivos
dc.contributor.authorBrito, Franciele Aline Machado de
dc.contributor.authorLaranjeira, Carlos
dc.contributor.authorMoroskoski, Marcia
dc.contributor.authorOliveira, Rosana Rosseto de
dc.contributor.authorSalci, Maria Aparecida
dc.contributor.authorRossoni, Stéfane Lele
dc.contributor.authorBaccon, Wanessa Cristina
dc.contributor.authorMarques, Priscila Garcia
dc.contributor.authorGóes, Herbert Leopoldo de Freitas
dc.contributor.authorMello, Fernanda Fontes
dc.contributor.authorBlaszczak, Flávia Renata Baldissera da Cruz
dc.contributor.authorVissoci, João Ricardo Nickenig
dc.contributor.authorAlcaraz, Jesús Puente
dc.contributor.authorFacchini, Luiz Augusto
dc.contributor.authorCarreira, Lígia
dc.date.accessioned2025-10-02T10:26:13Z
dc.date.available2025-10-02T10:26:13Z
dc.date.issued2025-01-23
dc.descriptionThis article belongs to the Special Issue Human Health Before, During, and After COVID-19 We acknowledge all the volunteers who made this study possible.
dc.descriptionArticle number - 228
dc.description.abstractBackground/Objectives: Currently, there is a limited understanding of the long-term consequences following acute COVID-19, referred to as long COVID. This cross-sectional study aims to analyze the prevalence of persistent signs and symptoms of long COVID, 18 months after primary SARS-CoV-2 infection in adults in southern Brazil. Methods: Using two national databases (the digital registry of SARS-CoV-2 positive cases), 370 individuals living in the state of Paraná (Brazil) were recruited. Data were collected through telephone interviews conducted in 2021 and 2022. Results: The overall prevalence of long COVID was 66.2% among study participants. During the acute phase of infection, the most common symptom clusters included neurological symptoms (87.0%; n = 318), followed by respiratory (82.0%; n = 301), musculoskeletal (66.0%; n = 241), digestive (50.0%; n = 184), psychological (38.0%; n = 138), and endocrine symptoms (28.0%; n = 104). In the 18 month follow-up, the main persistent symptoms were memory loss (42.7%), fatigue (32.2%), anxiety (23.5%), dyspnea (19.7%), and hair loss (19.7%). The proportion of participants with long COVID was statistically higher in females (73.9%), those with a family income below two minimum wages (94.7%), those who do not practice physical activity (83.3%), those who report poor sleep quality (93.3%), those who use long-term medication (85.9%), those who needed health care in the previous six months (87.3%), those who required professional and/or family care (79.3%), those who were in the ICU (79.0%), and those who used ventilatory support (77.5%). Conclusions: Long COVID is a complex condition that requires long-term monitoring and investment in health services due to its high prevalence and the health consequences in the population.eng
dc.description.sponsorshipThis work was funded by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)—grant number: 001/2023. It was also supported by FCT—Fundação para a Ciência e a Tecnologia, I.P. (UIDB/05704/2020 and UIDP/05704/2020) and by the Scientific Employment Stimulus—Institutional Call—[https://doi.org/10.54499/CEECINST/00051/2018/CP1566/CT0012].
dc.identifier.citationde Brito, F.A.M.; Laranjeira, C.; Moroskoski, M.; Salci, M.A.; Rossoni, S.L.; Baccon, W.C.; de Oliveira, R.R.; Marques, P.G.; de Freitas Góes, H.L.; Mello, F.F.; et al. Self-Reported Post-COVID Symptoms at 18 Months After Infection Among Adults in Southern Brazil: A Cross-Sectional Study. Healthcare 2025, 13, 228. https://doi.org/10.3390/healthcare13030228
dc.identifier.doi10.3390/healthcare13030228
dc.identifier.issn2227-9032
dc.identifier.urihttp://hdl.handle.net/10400.8/14183
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationCenter for Innovative Care and Health Technology
dc.relation.hasversionhttps://www.mdpi.com/2227-9032/13/3/228
dc.relation.ispartofHealthcare
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectBrazil
dc.subjectLong COVID
dc.subjectCross-sectional
dc.subjectSARS-CoV-2
dc.subjectSigns and symptoms
dc.titleSelf-Reported Post-COVID Symptoms at 18 Months After Infection Among Adults in Southern Brazil: A Cross-Sectional Studyeng
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCenter for Innovative Care and Health Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F05704%2F2020/PT
oaire.citation.issue3
oaire.citation.titleHealthcare
oaire.citation.volume13
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameLaranjeira
person.givenNameCarlos
person.identifier.orcid0000-0003-1080-9535
person.identifier.scopus-author-id22957802900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublication7c2157d8-cac9-4004-9438-e92fec260842
relation.isAuthorOfPublication.latestForDiscovery7c2157d8-cac9-4004-9438-e92fec260842
relation.isProjectOfPublicationd421b07d-3471-4026-aa43-def80b8e142b
relation.isProjectOfPublication.latestForDiscoveryd421b07d-3471-4026-aa43-def80b8e142b

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