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PCL/Eggshell Scaffolds for Bone Regeneration

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Resumo(s)

Eggshell (ES) is one of the most common biomaterials in nature. For instance, the ES represents 11% of the total weight of a hen’s egg and it is composed of calcium carbonate, magnesium carbonate, tricalcium phosphate and organic matter. Hen ES are also a major waste product of the food industry worldwide. Recently, ES have been used for many applications such as coating pigments for inkjet printing paper, catalyst for biodiesel synthesis, bio-fillers for polymer composites and matrix lipase immobilization. It is also considered a natural biomaterial with high potential for the synthesis of calcium enriched implants that may be applied in tissue engineering applications, such as bone regeneration. The aim of this research regards the production of poly(ε-caprolactone) (PCL) scaffolds enriched with hen ES powder for bone regeneration applications, using an extrusion-based process called Dual-Bioextruder. The main objective is to investigate the influence of the addition of ES powder on the PCL matrix. For this purpose the structures were characterised regarding morphological and chemical properties. Morphological images of the PCL scaffolds enriched with hen ES, demonstrated the interconnectivity of the pores within the scaffold and revealed that the addition of the ES powder combined with the screw rotation velocity has a large influence on the resulting filament diameter and consequently on the porosity of the scaffolds.

Descrição

Paper No: ESDA2014-20213.
Conferência: ESDA2014 - 12th Biennial Conference on Engineering Systems Design and Analysis. Data: 25 a 27 de junho de 2014.

Palavras-chave

Scaffolds Bone regeneration Eggshell Poly(ε-caprolactone) Tissue engineering Additive manufacturing

Contexto Educativo

Citação

Viana, T., Biscaia, S., Almeida, H. A., & Bártolo, P. J. (2014). PCL/Eggshell Scaffolds for Bone Regeneration. ASME 2014 12th Biennial Conference on Engineering Systems Design and Analysis. Volume 1: Advanced Energy Systems; Advanced Manufacturing; Biomedical Engineering; Design Engineering. ESDA2014-20213. https://doi.org/10.1115/ESDA2014-20213

Projetos de investigação

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Fascículo

Editora

American Society of Mechanical Engineers

Licença CC

Sem licença CC

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