Repository logo
 
Publication

New insights into the dermocosmetic potential of the red seaweed Gelidium corneum

2023Journal article Open access
Simple item page
dc.contributor.authorMatias, Margarida
dc.contributor.authorMartins, Alice
dc.contributor.authorAlves, Celso
dc.contributor.authorSilva, Joana
dc.contributor.authorPinteus, Susete
dc.contributor.authorFitas, Manuel
dc.contributor.authorPinto, Pedro
dc.contributor.authorMarto, Joana
dc.contributor.authorRibeiro, Helena
dc.contributor.authorMurray, Patrick
dc.contributor.authorPedrosa, Rui
dc.date.accessioned2023-11-29T10:45:02Z
dc.date.available2023-11-29T10:45:02Z
dc.date.issued2023
dc.descriptionThis work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018).pt_PT
dc.description.abstractThis work addresses the potential of the red seaweed Gelidium corneum as a source of bioactive ingredients for skin health and wellness in response to the growing awareness regarding the significance of sustainable strategies in developing new nature-based dermocosmetic products. Hydroalcoholic extracts from the dried biomass were subjected to sequential liquid–liquid partitions, affording five different fractions (F1–F5). Their cosmetic potential was assessed through a set of in vitro assays concerning their antioxidant, photoprotective, and healing properties. Additionally, their cytotoxicity in HaCaT cells and their capacity to induce inflammation in RAW 264.7 cells were also evaluated. As a proof-of-concept, O/W emulsions were prepared, and emulsion stability was assessed by optical microscopy, droplet size analysis, centrifugation tests, and rheology analysis. Furthermore, in vivo tests were conducted with the final formulation to assess its antioxidant capacity. At subtoxic concentrations, the most lipophilic fraction has provided photoprotection against UV light-induced photooxidation in HaCaT cells. This was conducted together with the aqueous fraction, which also displayed healing capacities. Regarding the physical and stability assays, the best performance was achieved with the formulation containing 1% aqueous extract, which exhibited water retention and antioxidant properties in the in vivo assay. In summary, Gelidium corneum displayed itself as a potential source of bioactive ingredients with multitarget properties for dermatological use.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMatias, M.; Martins, A.; Alves, C.; Silva, J.; Pinteus, S.; Fitas, M.; Pinto, P.; Marto, J.; Ribeiro, H.; Murray, P.; et al. New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum. Antioxidants 2023, 12, 1684. https:// doi.org/10.3390/antiox12091684pt_PT
dc.identifier.doi10.3390/antiox12091684pt_PT
dc.identifier.issn2076-3921
dc.identifier.urihttp://hdl.handle.net/10400.8/8973
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationMarine and Environmental Sciences Centre
dc.relationMarine and Environmental Sciences Centre
dc.relationAquatic Research Infrastructure Network
dc.relationResearch Institute for Medicines
dc.relationResearch Institute for Medicines
dc.relation.publisherversionhttps://www.mdpi.com/2076-3921/12/9/1684pt_PT
dc.subjectGelidium corneumpt_PT
dc.subjectGreener skincare productspt_PT
dc.subjectMarine natural productspt_PT
dc.subjectAntioxidant capacitypt_PT
dc.subjectPhotoprotectionpt_PT
dc.subjectWound healingpt_PT
dc.subjectTopical formulationspt_PT
dc.subjectIn vivo compatibilitypt_PT
dc.titleNew insights into the dermocosmetic potential of the red seaweed Gelidium corneumpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMarine and Environmental Sciences Centre
oaire.awardTitleMarine and Environmental Sciences Centre
oaire.awardTitleAquatic Research Infrastructure Network
oaire.awardTitleResearch Institute for Medicines
oaire.awardTitleResearch Institute for Medicines
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04292%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04292%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0069%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04138%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04138%2F2020/PT
oaire.citation.issue9pt_PT
oaire.citation.titleAntioxidantspt_PT
oaire.citation.volume12pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMoreira Fernandes Matias
person.familyNameMartins
person.familyNameAlves
person.familyNameSilva
person.familyNamePinteus
person.familyNamePinto
person.familyNameMarques Marto
person.familyNameRibeiro
person.familyNameMurray
person.familyNamePedrosa
person.givenNameMargarida
person.givenNameAlice
person.givenNameCelso
person.givenNameJoana
person.givenNameSusete
person.givenNamePedro
person.givenNameJoana
person.givenNameHelena
person.givenNamePatrick
person.givenNameRui
person.identifier159091
person.identifier98885
person.identifier159292
person.identifier1570599
person.identifier349272
person.identifier.ciencia-id2B11-AC77-D7F9
person.identifier.ciencia-idDA19-728A-9BC8
person.identifier.ciencia-id501C-F268-2E60
person.identifier.ciencia-id6317-6F15-BA35
person.identifier.ciencia-id661E-9677-74C5
person.identifier.ciencia-id8D15-FEBC-C15C
person.identifier.ciencia-id891B-12E1-C2BF
person.identifier.ciencia-id161F-B79B-D660
person.identifier.ciencia-idEB1B-6C0D-DAF7
person.identifier.ciencia-id3817-33DE-919E
person.identifier.orcid0000-0002-8866-2564
person.identifier.orcid0000-0002-0542-2662
person.identifier.orcid0000-0003-1581-2127
person.identifier.orcid0000-0003-1224-1699
person.identifier.orcid0000-0002-3290-3111
person.identifier.orcid0000-0002-5723-0750
person.identifier.orcid0000-0001-5523-5622
person.identifier.orcid0000-0002-2429-7991
person.identifier.orcid0000-0001-6349-7761
person.identifier.orcid0000-0003-0970-0575
person.identifier.ridB-3366-2017
person.identifier.ridE-6315-2014
person.identifier.ridE-2944-2015
person.identifier.ridB-4815-2015
person.identifier.scopus-author-id56013514200
person.identifier.scopus-author-id55654969100
person.identifier.scopus-author-id56370819800
person.identifier.scopus-author-id55655328300
person.identifier.scopus-author-id7801585708
person.identifier.scopus-author-id35896704400
person.identifier.scopus-author-id7005010300
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication147472b0-a465-4250-8c4a-884235a973d3
relation.isAuthorOfPublication1bc1a00d-0af9-4be5-b19f-ddaf89268517
relation.isAuthorOfPublicationba5ab7c2-7474-4ea9-9bf0-ca15fe42809a
relation.isAuthorOfPublication23e68f76-0f7a-4f39-9da8-f1a26e2e2cd7
relation.isAuthorOfPublicationdb45e9a7-9e25-4fbf-903e-9feac4a23d61
relation.isAuthorOfPublication6395f94f-f1a5-483e-b069-0bcc436a5812
relation.isAuthorOfPublication666194f3-de6f-4ebc-b00b-2ba24b5ac422
relation.isAuthorOfPublication51734878-db02-4a67-906d-a0161ed2e2dc
relation.isAuthorOfPublicationc698a8b4-18a5-43ca-a37d-883c764fa579
relation.isAuthorOfPublication94496a40-57cf-472f-94e1-5db9d5da78b6
relation.isAuthorOfPublication.latestForDiscovery147472b0-a465-4250-8c4a-884235a973d3
relation.isProjectOfPublicationa66a15eb-ff92-44d8-a34e-0f87f0c01d01
relation.isProjectOfPublication54154db1-7a14-4ce1-b54e-b3a01fcd44f5
relation.isProjectOfPublication2b6d255a-da1a-4dc7-b08f-361bcf19995e
relation.isProjectOfPublicationaa2f47fc-ea1a-438c-956c-6f267577bb13
relation.isProjectOfPublication58663eca-55b0-49c1-b5fb-51a6b39868d9
relation.isProjectOfPublication.latestForDiscovery2b6d255a-da1a-4dc7-b08f-361bcf19995e

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Matias et al_2023_New insights into the_antioxidants-12-01684-v2.pdf
Size:
3.75 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.32 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

MARE - Artigos com peer review
ESTM - Artigos em revistas internacionais