| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| Additive manufacturing involves the shaping of a product through the use of a liquid phase which is subsequently transformed to the solid state by cooling or through the use of chemical cross-linking reactions. Of particular note is the fused deposition modeling which utilizes semi-crystalline polymers such as poly(ε-caprolactone) or poly(lactic acid) and has been employed in CDRsp to prepare highly porous scaffolds for Tissue Engineering. We show that the crystallization process amplifies small levels of molecular anisotropy introduced in the additive writing process. We show that the level of anisotropy is significantly dependent on the process parameters such as temperature, write speed, and flow rate. The differences in the crystalline morphology introduced by changing these process parameters will have a marked impact on the mechanical properties. This in turn will alter the growth of tissue on such scaffold structures. As with other polymer processing procedures, tuning the process parameters provides a route to controlling and defining the structure and morphology of the scaffold and the properties exhibited by that scaffold. | 597.75 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Additive manufacturing involves the shaping of a product through the use of a liquid phase which is subsequently transformed to the solid state by cooling or through the use of chemical cross-linking reactions. Of particular note is the fused deposition modeling which utilizes semi-crystalline polymers such as poly(ε-caprolactone) or poly(lactic acid) and has been employed in CDRsp to prepare highly porous scaffolds for Tissue Engineering. We show that the crystallization process amplifies small levels of molecular anisotropy introduced in the additive writing process. We show that the level of anisotropy is significantly dependent on the process parameters such as temperature, write speed, and flow rate. The differences in the crystalline morphology introduced by changing these process parameters will have a marked impact on the mechanical properties. This in turn will alter the growth of tissue on such scaffold structures. As with other polymer processing procedures, tuning the process parameters provides a route to controlling and defining the structure and morphology of the scaffold and the properties exhibited by that scaffold.
Descrição
Conference date - 1 October 2013 - 5 October 2013; Conference code - 101946
Palavras-chave
3D printers Anisotropy Crosslinking Manufacture Mechanical properties Rapid prototyping Scaffolds (biology)
Contexto Educativo
Citação
Tojeira, A., Biscaia, S., Viana, T., Bártolo, P. J., & Mitchell, G. R. (2013). Structure development during additive manufacturing. High Value Manufacturing–VRAP.
Editora
Taylor and Francis
Licença CC
Sem licença CC
