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Osteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionals

dc.contributor.authorMorouço, Pedro
dc.contributor.authorFernandes, Cristiana
dc.contributor.authorSantos-Rocha, Rita
dc.date.accessioned2023-04-26T14:43:06Z
dc.date.available2023-04-26T14:43:06Z
dc.date.issued2019
dc.descriptionAcknowledgments: This research was supported by the European Regional Development Fund (FEDER), through COMPETE2020 under the PT2020 program (POCI-01-0145-FEDER-023423), and by the Portuguese Foundation for Science and Technology (UID/Multi/04044/2019).pt_PT
dc.description.abstractOsteoarthritis (OA) is a degenerative disease, promoted by abnormal chronic mechanical loading over the joint, for instance, due to excessive body mass. Patients frequently report pain, fatigue, and limitations in specific functional daily activities. Regarding the treatment of OA, two nonpharmacological options are available. However, it is not clear which type and intensity of exercise have better outcomes in treatment and how tissue engineering can be a promising field due to the mechanical load implants will suffer. The aims of this work were to investigate (1) the main characteristics, prevalence, and consequences of OA; (2) the exercise prescription guidelines and whether exercise interventions have a positive effect on OA treatment; and (3) the novel improvements on tissue engineering for OA treatment. Both patients and practitioners should be aware that benefits may come from prescribed and supervised exercise. Recent studies have highlighted that an optimal balance between exercise and nutritional income should be widely recommended. Regarding tissue engineering, significant steps towards the development of implants that mimic the native tissue have been taken. Thus, further studies should focus on the impact that exercise (repetitive loading) might have on cartilage regeneration. Finally, suggestions for future research were proposed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPedro Morouço, Cristiana Fernandes, Rita Santos-Rocha, "Osteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionals", Journal of Aging Research, vol. 2019, Article ID 1935806, 6 pages, 2019. https://doi.org/10.1155/2019/1935806pt_PT
dc.identifier.doihttps://doi.org/10.1155/2019/1935806pt_PT
dc.identifier.eissn2090-2212
dc.identifier.issn2090-2204
dc.identifier.other1935806
dc.identifier.urihttp://hdl.handle.net/10400.8/8454
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHindawipt_PT
dc.relationCentre for Rapid and Sustainable Product Development
dc.relation.publisherversionhttps://www.hindawi.com/journals/jar/2019/1935806/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleOsteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionalspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre for Rapid and Sustainable Product Development
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F04044%2F2019/PT
oaire.citation.endPage6pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleJournal of Aging Researchpt_PT
oaire.citation.volume2019pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMorouço
person.familyNameFernandes
person.givenNamePedro
person.givenNameCristiana Henriques
person.identifier435983
person.identifier.ciencia-idF619-3996-742A
person.identifier.ciencia-id0C18-D3D1-D625
person.identifier.orcid0000-0002-5956-9790
person.identifier.orcid0000-0001-6371-800X
person.identifier.ridK-9545-2013
person.identifier.scopus-author-id24339135400
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscovery05b28d80-9e18-41cc-a66c-f37955bfc8da
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