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Efeito anti-placa de bochechos no crescimento de placa bacteriana supra-gengival: um ensaio clínico aleatório
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Advisor(s)
Abstract(s)
Objetivo: O objetivo deste estudo foi o de avaliar o efeito antiplaca de um bochecho com óleos essenciais (EO) sem álcool e de um bochecho de cloreto de cetilpiridínio (CPC) em comparação com um controlo positivo de clorohexidina (CHX), utilizando um modelo in vivo de crescimento de placa bacteriana durante três dias.
Métodos: Este estudo foi desenvolvido como um ensaio clínico cruzado, cego e aleatorizado, que envolveu 16 voluntários. Após receberem a profilaxia profissional, durante os três dias seguintes, cada voluntário deixou de utilizar qualquer outro meio de higiene oral e realizou dois bochechos diários com 20 ml de um dos colutórios em teste. O bochecho de clorohexidina a 0,2% foi utilizado como controlo positivo. Após os três dias, o índice de placa foi avaliado e os participantes preencheram um questionário para manifestar a opinião em relação ao produto utilizado. Cada voluntário passou por um período de washout de 14 dias entre cada fase do estudo.
Resultados: O grupo que utilizou o CPC mostrou um melhor efeito na inibição do crescimento da placa bacteriana, quando comparado com o grupo EO. De facto, a média global do índice de placa bacteriana foi menor com a utilização do CPC (1,30) do que com o uso do EO (1,73) e da CHX (1,54). Todos estes valores foram estatisticamente significativos (P<0,031).
Conclusão: O CPC apresentou melhores resultados na redução da placa bacteriana quando comparado com o EO e com a CHX.
Objective: The aim of this study was to evaluate the antiplaque effects of an alcohol-free essential-oil (EO) mouthwash and a cetylpyridinium chloride (CPC) mouthwash compared to a chlorhexidine (CHX) mouthwash as a positive control, using an in-vivo plaque regrowth model of 3 days. Methods: The study was designed as a masked, randomized, crossover clinical trial, involving 16 volunteers. After receiving thorough professional prophylaxis at baseline, over the next 3 days, each volunteer refrained from all other oral hygiene measures and performed two daily rinses with 20 ml of the test mouthwashes. A 0.20% chlorhexidine rinse served as a positive control. After 3 days, the plaque index was evaluated, and the participants answered a questionnaire on their opinion about the product used. Each subject underwent a 14-day washout period and, then, there was another allocation. Results: The CPC group showed a better effect on the inhibition of plaque growth than the EO group. In fact, the overall mean plaque index was lower with CPC (1.30) than with EO (1.73) and CHX (1.54). All these values were statistically significant (P<0.031). Conclusion: The CPC had better results in reducing bacterial plaque than EO and CHX.
Objective: The aim of this study was to evaluate the antiplaque effects of an alcohol-free essential-oil (EO) mouthwash and a cetylpyridinium chloride (CPC) mouthwash compared to a chlorhexidine (CHX) mouthwash as a positive control, using an in-vivo plaque regrowth model of 3 days. Methods: The study was designed as a masked, randomized, crossover clinical trial, involving 16 volunteers. After receiving thorough professional prophylaxis at baseline, over the next 3 days, each volunteer refrained from all other oral hygiene measures and performed two daily rinses with 20 ml of the test mouthwashes. A 0.20% chlorhexidine rinse served as a positive control. After 3 days, the plaque index was evaluated, and the participants answered a questionnaire on their opinion about the product used. Each subject underwent a 14-day washout period and, then, there was another allocation. Results: The CPC group showed a better effect on the inhibition of plaque growth than the EO group. In fact, the overall mean plaque index was lower with CPC (1.30) than with EO (1.73) and CHX (1.54). All these values were statistically significant (P<0.031). Conclusion: The CPC had better results in reducing bacterial plaque than EO and CHX.
Description
Keywords
Cloreto de cetilpiridínio Clorhexidina Colutórios Óleo essencial Placa bacteriana Sem álcool Cetylpyridinium chloride Chlorhexidine Mouthwashes Essential oils Dental plaque Alcohol free
Pedagogical Context
Citation
Tarlattini, Giovanna & Ribeiro, Sandra & Albuquerque, Teresa & Luis, Henrique. (2018). Efeito anti-placa de bochechos no crescimento de placa bacteriana supra-gengival: um ensaio clínico aleatório. Revista portuguesa de estomatologia e cirurgia maxilo-facial. 59. 10.24873/j.rpemd.2018.11.418.
Publisher
Sociedade Portuguesa de Estomatologia e Medicina Dentaria (SPEMD)