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Monthly follow-ups of functional status inpeople with COPD: A longitudinal study

2022Journal article Open access
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dc.contributor.authorRocha, Vânia
dc.contributor.authorCabral, Jorge
dc.contributor.authorSouto-Miranda, Sara
dc.contributor.authorMachado, Ana Filipa
dc.contributor.authorCristina, Jácome
dc.contributor.authorCruz, Joana
dc.contributor.authorMartins, Vitória
dc.contributor.authorSimão, Paula
dc.contributor.authorMendes, Maria Aurora
dc.contributor.authorAfreixo, Vera
dc.contributor.authorMarques, Alda
dc.date.accessioned2022-07-05T12:29:19Z
dc.date.available2022-07-05T12:29:19Z
dc.date.issued2022
dc.description.abstractFunctional status is an important and meaningful outcome in people with chronic obstructive pulmonary disease (COPD), although its measurement is not embedded in routine clinical assessments. This study described the functional status of people with COPD using the 1-min sit-to-stand test (1minSTS) over a 6-month period and the examined sociodemographic and clinical characteristics associated with this outcome. Data from a prospective study including people with COPD were analyzed. Functional status was assessed monthly with the 1minSTS over 6 months. Linear-mixed effect models assessed the 1minSTS number of repetitions mean change. One-hundred and eight participants (82.4% men; 66.9 +-9.5 years) were included. A significantly lower number of repetitions in the 1minSTS over the 6-month period was associated with being female (estimate: -4.69, 95%CI: -8.20; -1.18), being older (estimate: -0.56, 95%CI: -0.77; -0.34), having higher BMI (estimate: -0.55, 95%CI: -0.81; -0.28) and having higher activity-related dyspnea (estimate: -2.04, 95%CI: -3.25; -0.83). Half of the participants showed improvements above three repetitions in the 1minSTS over the 6-month period, independently of their baseline impairment (1minSTS < 70% predicted: 52.5%; 70% predicted: 54.4%). To conclude, monthly follow-up assessments were associated with clinically relevant benefits in the functional status of people with COPD. Age, body composition, and activity-related dyspnea were the main predictors of functional status over time. Further research is needed to corroborate our findings and to support the beneficial effects of regular COPD monitoring.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRocha, V.; Cabral, J.; Souto-Miranda, S.; Machado, A.F.; Jácome, C.; Cruz, J.; Martins, V.; Simão, P.; Mendes, M.A.; Afreixo, V.; et al. Monthly Follow-Ups of Functional Status in People with COPD: A Longitudinal Study. J. Clin. Med. 2022, 11, 3052. https:// doi.org/10.3390/jcm11113052pt_PT
dc.identifier.doi10.3390/jcm11113052pt_PT
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10400.8/7324
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationPOCI-01-0145-FEDER-028806pt_PT
dc.relationAveiro Institute of Biomedicine
dc.relationCenter for Research and Development in Mathematics and Applications
dc.relationCenter for Research and Development in Mathematics and Applications
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCOPDpt_PT
dc.subjectFunctional statuspt_PT
dc.subjectsit-to-standpt_PT
dc.subjectLongitudinal studypt_PT
dc.subjectField testspt_PT
dc.subjectEvaluation and monitoringpt_PT
dc.titleMonthly follow-ups of functional status inpeople with COPD: A longitudinal studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAveiro Institute of Biomedicine
oaire.awardTitleCenter for Research and Development in Mathematics and Applications
oaire.awardTitleCenter for Research and Development in Mathematics and Applications
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FSAU-SER%2F28806%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04501%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04106%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04106%2F2020/PT
oaire.citation.titleJournal of Clinical Medicinept_PT
oaire.citation.volume11pt_PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMartins Rocha
person.familyNameVaz Ramos Rodrigues de Cabral
person.familyNamePalos Souto de Miranda
person.familyNameMarques Rego Machado
person.familyNameJácome
person.familyNameCruz
person.familyNameAfreixo
person.familyNameMarques
person.givenNameVânia Patrícia
person.givenNameJorge
person.givenNameSara
person.givenNameAna Filipa
person.givenNameCristina
person.givenNameJoana
person.givenNameVera
person.givenNameAlda
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person.identifier.orcid0000-0002-4911-4469
person.identifier.orcid0000-0003-1051-8084
person.identifier.orcid0000-0003-4980-6200
person.identifier.ridK-4641-2013
person.identifier.ridK-7030-2013
person.identifier.scopus-author-id26635339900
person.identifier.scopus-author-id36715922000
project.funder.identifierhttp://doi.org/10.13039/501100001871
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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