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Alginate/Aloe Vera Hydrogel Films for Biomedical Applications

2013Comunicação em conferência Acesso aberto
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datacite.subject.fosCiências Médicas::Biotecnologia Médica
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorPereira, Rúben F.
dc.contributor.authorMendes, Ausenda
dc.contributor.authorBártolo, Paulo
dc.date.accessioned2026-03-23T17:43:58Z
dc.date.available2026-03-23T17:43:58Z
dc.date.issued2013
dc.description.abstractThis paper describes a methodology to produce hydrogel films, composed of alginate and Aloe vera, for wound healing and drug delivery applications. The films were prepared through the solvent-casting method and subsequently submitted to an additional cross-linking step to improve their properties. Alginate films with different Aloe vera contents (5, 15 and 25%) were prepared and its properties evaluated in terms of thickness, transparency, swelling behavior and in vitro degradation. Results show a positive influence of Aloe vera on the transparency of the films, in both dry and wet state. Films were immersed in acetate buffer at pH 5.5 simulating the value of the skin, to evaluate its water absorption capacity. It was found that water absorption increases as the Aloe vera content increases, suggesting that Aloe vera enhances the hydrophilic properties of the films. The in vitro degradation tests were performed through the incubation of the films, for 10 weeks, in a simulated body fluid at 37°C. After this period, films kept its structure integrity exhibiting a weight loss in the range of 14.1-18.6%.eng
dc.description.sponsorshipThis research work was supported by the Portuguese Foundation for Science and Technology through the strategic project Pest-OE/EME/UI4044/2011.
dc.identifier.citationúben Pereira, Ausenda Mendes, Paulo Bártolo, Alginate/Aloe Vera Hydrogel Films for Biomedical Applications, Procedia CIRP, Volume 5, 2013, Pages 210-215, ISSN 2212-8271, https://doi.org/10.1016/j.procir.2013.01.042.
dc.identifier.doi10.1016/j.procir.2013.01.042
dc.identifier.issn2212-8271
dc.identifier.urihttp://hdl.handle.net/10400.8/15952
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S2212827113000437?via%3Dihub
dc.relation.ispartofProcedia CIRP
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAlginate
dc.subjectAloe vera
dc.subjectFilms
dc.subjectHydrogels
dc.subjectWound healing
dc.titleAlginate/Aloe Vera Hydrogel Films for Biomedical Applicationseng
dc.typeconference paper
dspace.entity.typePublication
oaire.awardNumberPEst-OE/EME/UI4044/2011
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.conferenceDate2013
oaire.citation.endPage215
oaire.citation.startPage210
oaire.citation.titleProcedia CIRP
oaire.citation.volume5
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameBrás Pereira
person.familyNameMendes
person.familyNameBartolo
person.givenNameRúben Filipe
person.givenNameAusenda
person.givenNamePaulo
person.identifier1337969
person.identifier203086
person.identifier.ciencia-id9417-153E-4473
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-7255-3400
person.identifier.orcid0000-0003-3004-8972
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridP-8503-2018
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55421048100
person.identifier.scopus-author-id7102443940
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationeda35774-59b3-4801-aa88-9c20f4c31a78
relation.isAuthorOfPublication5ac3b700-95c6-4782-861a-deea8e449a7c
relation.isAuthorOfPublicationab44d1ae-46d0-45c2-b19f-200024b5a990
relation.isAuthorOfPublication.latestForDiscoveryeda35774-59b3-4801-aa88-9c20f4c31a78
relation.isProjectOfPublication44bd1c93-9ee1-4685-a408-c2baa61ffbcd
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