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The Combined Effect of the Mediterranean Diet and Physical Activity on the Components of Metabolic Syndrome in Adults: A Systematic Review of Randomised Controlled Trials

dc.contributor.authorTeixeira, Luíza
dc.contributor.authorMonteiro, Diogo
dc.contributor.authorMatos, Rui
dc.contributor.authorSusano Jacinto, Miguel Ângelo
dc.contributor.authorAntunes, Raul
dc.date.accessioned2025-09-26T17:23:15Z
dc.date.available2025-09-26T17:23:15Z
dc.date.issued2025-09-25en_US
dc.date.updated2025-09-26T08:53:24Z
dc.description.abstractMetabolic syndrome (MetS) is a global public health challenge, characterized by the coexistence of cardiometabolic risk factors such as abdominal obesity, dyslipidaemia, hypertension, and insulin resistance. Non-pharmacological strategies, including the Mediterranean diet (MD) and physical activity (PA), have been widely studied for their potential to prevent and manage MetS. This systematic review aimed to synthesize the evidence on the combined effect of MD and PA on MetS components in adults, based on randomized controlled trials (RCTs). Twenty-two RCTs published between 2018 and 2024 were included, involving 11,478 participants. The interventions ranged from 8 weeks to 3 years and combined adapted or hypocaloric MDs with moderate-to-high-intensity PA, typically including walking, aerobic exercise, or high-intensity interval training (HIIT), performed 3 to 7 times per week. The combined interventions resulted in reductions in body weight (−2.5 to −7.2 kg), body mass index (−0.7 to −2.2 kg/m2), waist circumference (−5.1 to −7.8 cm), and blood pressure (up to −9.0 mmHg systolic and −6.7 mmHg diastolic). Improvements in HDL cholesterol, triglyceride levels, and insulin sensitivity were also observed. These findings suggest that integrated interventions based on the Mediterranean lifestyle are effective in reducing MetS components and may support future public health strategies.eng
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationTeixeira, L., Monteiro, D., Matos, R., Antunes, R., & Jacinto, M. (2025). The Combined Effect of the Mediterranean Diet and Physical Activity on the Components of Metabolic Syndrome in Adults: A Systematic Review of Randomised Controlled Trials. Obesities, 5(4), 68. https://doi.org/10.3390/obesities5040068
dc.identifier.doihttps://doi.org/10.3390/obesities5040068en_US
dc.identifier.issn2673-4168
dc.identifier.slugcv-prod-4570389
dc.identifier.urihttp://hdl.handle.net/10400.8/14139
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationUID/04045
dc.relation.hasversionhttps://www.mdpi.com/2673-4168/5/4/68
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectmediterranean dieten_US
dc.subjectphysical activityen_US
dc.subjectmetabolic syndromeen_US
dc.subjectcardiometabolic risken_US
dc.subjectinsulin resistanceen_US
dc.subjectabdominal obesityen_US
dc.titleThe Combined Effect of the Mediterranean Diet and Physical Activity on the Components of Metabolic Syndrome in Adults: A Systematic Review of Randomised Controlled Trialseng
dc.typeresearch articleen_US
dspace.entity.typePublication
oaire.citation.issue4en_US
oaire.citation.startPage68
oaire.citation.titleObesitiesen_US
oaire.citation.volume5en_US
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameMonteiro
person.familyNameMatos
person.familyNameSusano Jacinto
person.familyNameAntunes
person.givenNameDiogo
person.givenNameRui
person.givenNameMiguel Ângelo
person.givenNameRaul
person.identifierF-1202-2015
person.identifier.ciencia-idED1F-6228-E26F
person.identifier.ciencia-idE91C-D6C7-62A5
person.identifier.ciencia-id0816-8EAF-D4D1
person.identifier.ciencia-id8B16-73A3-A66E
person.identifier.orcid0000-0002-7179-6814
person.identifier.orcid0000-0002-2034-0585
person.identifier.orcid0000-0002-1727-3537
person.identifier.orcid0000-0002-5485-9430
person.identifier.scopus-author-id56437945500
person.identifier.scopus-author-id55315503400
person.identifier.scopus-author-id57194044687
rcaap.cv.cienciaidED1F-6228-E26F | Diogo Monteiro
rcaap.rightsopenAccessen_US
relation.isAuthorOfPublication79dcae83-d54a-4acc-a9a1-8268c7776ab9
relation.isAuthorOfPublication28ca4c61-3386-4b73-9eef-c377816d5a31
relation.isAuthorOfPublicationab5535bd-950a-4507-968c-2fab33b83223
relation.isAuthorOfPublication292d3773-ef00-4441-a4b8-9f53e3cba456
relation.isAuthorOfPublication.latestForDiscovery79dcae83-d54a-4acc-a9a1-8268c7776ab9

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