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Publication
Common evaluations of disease activity in rheumatoid arthritis reach discordant classifications across different populations
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Advisor(s)
Abstract(s)
The classification of disease activity states in rheumatoid arthritis (RA) can be achieved through disease activity indices, such as the Disease Activity Score in 28 joints erythrocyte sedimentation rate (DAS28-ESR), the Simplified Disease Activity Index (SDAI), and the Clinical Disease Activity Index (CDAI). Subjective measurements, such as patient reported outcomes have been incorporated into several of these indices alongside more objective assessments, such as increases in the ESR and C-reactive protein. Moreover, while they use similar criteria, different indices weight these criteria to different extents. Therefore, the classifications based on each evaluation may not always be the same. We aim to compare the performance of the three indices and their individual components in two different populations.
Description
Keywords
Rheumatoid arthritis Patient reported outcomes Physicians’ perspective Acute phase reactants DAS28-ESR METEOR
Citation
Canhão, H., Rodrigues, A. M., Gregório, M. J., Dias, S. S., Melo Gomes, J. A., Santos, M. J., … & van der Heijde, D. (2018). Common evaluations of disease activity in rheumatoid arthritis reach discordant classifications across different populations. Frontiers in Medicine, 5, 40. doi: 3389/fmed.2018.00040