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Permeability Evaluation of Flow Behaviors Within Perfusion Bioreactors

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datacite.subject.fosEngenharia e Tecnologia
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
dc.contributor.authorFreitas, D.
dc.contributor.authorAlmeida, H.A.
dc.contributor.authorBártolo, P. J.
dc.date.accessioned2025-12-15T15:40:09Z
dc.date.available2025-12-15T15:40:09Z
dc.date.issued2015
dc.descriptionConference name 5th European Conference on Mechanism Science, EUCOMES 2014, Guimarães
dc.descriptionConference date 16 September 2014 - 19 September 2014
dc.description.abstractTissue engineering aims to produce artificial tissue in order to create or repair damaged tissue. It is evident that scaffolds are of extreme importance, because they will be the support structure of the new tissue. This new tissue is cultivated in vitro in a bioreactor in which is placed the scaffold. In order to control the cell culture process inside of a bioreactor, it is essential to know the fluid flow inside the scaffold for an adequate exchange of nutrients and metabolic waste. A novel multifunctional bioreactor with a perfusion system module comprised of three different inlet and outlet membranes is being developed. This research work will evaluate the permeability of the scaffold under the three different inlet and outlet diffusion membranes of the culture chamber.eng
dc.description.sponsorshipFunding text The authors acknowledge the support of the Strategic Project (PEST-OE/EME/UI4044/2013) funded by the Portuguese Foundation for Science and Technology. Authors also acknowledge the support of the European Commission through the Marie Curie Project “International Research Exchange for Biomedical Devices De-sign and Prototyping” “IREBID”.
dc.identifier.citationFreitas, D., Almeida, H.A., Bártolo, P.J. (2015). Permeability Evaluation of Flow Behaviors Within Perfusion Bioreactors. In: Flores, P., Viadero, F. (eds), New Trends in Mechanism and Machine Science. Mechanisms and Machine Science, vol 24. Springer, Cham. https://doi.org/10.1007/978-3-319-09411-3_80
dc.identifier.doi10.1007/978-3-319-09411-3_80
dc.identifier.isbn9783319094106
dc.identifier.isbn9783319094113
dc.identifier.issn2211-0984
dc.identifier.issn2211-0992
dc.identifier.urihttp://hdl.handle.net/10400.8/15055
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Nature
dc.relationStrategic Project - UI 4044 - 2013-2014
dc.relation.hasversionhttps://link.springer.com/chapter/10.1007/978-3-319-09411-3_80
dc.relation.ispartofMechanisms and Machine Science
dc.relation.ispartofNew Trends in Mechanism and Machine Science
dc.rights.uriN/A
dc.subjectBioreactor design
dc.subjectFlow behavior
dc.subjectNumerical simulation
dc.subjectPermeability
dc.subjectScaffold
dc.titlePermeability Evaluation of Flow Behaviors Within Perfusion Bioreactors
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 4044 - 2013-2014
oaire.awardURIhttp://hdl.handle.net/10400.8/13452
oaire.citation.endPage768
oaire.citation.startPage761
oaire.citation.titleNew Trends in Mechanism and Machine Science
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameFreitas
person.familyNameAlmeida
person.familyNameBartolo
person.givenNameDino
person.givenNameHenrique de Amorim
person.givenNamePaulo
person.identifier133710
person.identifier46395
person.identifier203086
person.identifier.ciencia-id1A1F-4FE8-9D40
person.identifier.ciencia-id8F1D-4370-84BE
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0003-1094-8527
person.identifier.orcid0000-0002-1367-2290
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridN-7893-2015
person.identifier.ridD-6275-2012
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55795311300
person.identifier.scopus-author-id55938867800
person.identifier.scopus-author-id6603353041
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