Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy

Kariduraganavar, Mahadevappa Y.; Heggannavar, Geetha B.; Amado, Sandra; Mitchell, Geoffrey R.

http://hdl.handle.net/10400.8/8615

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Authors

Kariduraganavar, Mahadevappa Y.

Heggannavar, Geetha B.

Amado, Sandra

Mitchell, Geoffrey R.

Abstract(s)

This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted.

Keywords

Cancer therapy Drug delivery Nanoparticles Proteins Targeted delivery

URI

http://hdl.handle.net/10400.8/8615

Citation

Mahadevappa Y. Kariduraganavar, Geetha B. Heggannavar, Sandra Amado, Geoffrey R. Mitchell, Chapter 6 - Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy, Editor(s): Shyam S. Mohapatra, Shivendu Ranjan, Nandita Dasgupta, Raghvendra Kumar Mishra, Sabu Thomas, In Micro and Nano Technologies, Nanocarriers for Drug Delivery, Elsevier, 2019, Pages 173-204, ISBN 9780128140338, https://doi.org/10.1016/B978-0-12-814033-8.00006-0