Repository logo
 
Publication

Detection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli and Salmonella enterica isolated from poultry and swine in Spain

2016-04Journal article Restricted access
Simple item page
datacite.subject.sdg12:Produção e Consumo Sustentáveis
datacite.subject.sdg13:Ação Climática
datacite.subject.sdg14:Proteger a Vida Marinha
dc.contributor.authorQuesada, Alberto
dc.contributor.authorUgarte-Ruiz, María
dc.contributor.authorIglesias, M. Rocío
dc.contributor.authorPorrero, M. Concepción
dc.contributor.authorMartínez, Remigio
dc.contributor.authorFlorez-Cuadrado, Diego
dc.contributor.authorCampos, Maria J.
dc.contributor.authorGarcía, María
dc.contributor.authorPíriz, Segundo
dc.contributor.authorSáez, José Luis
dc.contributor.authorDomínguez, Lucas
dc.date.accessioned2025-06-06T15:03:30Z
dc.date.available2025-06-06T15:03:30Z
dc.date.issued2016-04
dc.description.abstractRecent findings suggest that use of colistin as a last resort antibiotic is seriously threatened by the rise of a new plasmid mediated mechanism of resistance (MCR-1). This work identifies, for the first time in Southern Europe, the gene mcr-1 in nine strains from farm animals (poultry and swine) corresponding to five Escherichia coli and four Salmonella enterica, amongwhich three belong to serovar Typhimuriumand one to Rissen. TheMCR-1 was found encoded by a plasmid highly mobilizable by conjugation to the E. coli J53 strain. Two E. coli strains carried two determinants, mcr-1 plus pmrA or pmrB mutations, known to confer colistin resistance.eng
dc.description.sponsorshipThiswork has been supported by the Ministry of Innovation, Science and Technology of Spain (AGL2012-39028-C03-01 and AGL2012-39028-C03-03), the Department of Employ, Enterprise and Innovation of the Regional Government of Extremadura, Spain (Group CTS001), theUniversity of Extremadura (GroupMIVET), and the SpanishMinistry of Agriculture, Food and Environment and the Autonomous Community of Madrid, Spain (S2013/ABI-2747).M.R.I. and D.F.-C. wish to thank, for their respective PhD fellowships, the “Fundación Tatiana Pérez de Guzmán el Bueno” and to the FPI programme (BES-2013-065003) of the Spanish Ministry of Economy and Competitiveness.
dc.identifier.citationQuesada A, Ugarte-Ruiz M, Iglesias MR, Porrero MC, Martínez R, Florez-Cuadrado D, Campos MJ, García M, Píriz S, Sáez JL, Domínguez L. Detection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli and Salmonella enterica isolated from poultry and swine in Spain. Res Vet Sci. 2016 Apr;105:134-5. doi: 10.1016/j.rvsc.2016.02.003
dc.identifier.doi10.1016/j.rvsc.2016.02.003
dc.identifier.issn0034-5288
dc.identifier.urihttp://hdl.handle.net/10400.8/13170
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier BV
dc.relation.hasversionhttps://pubmed.ncbi.nlm.nih.gov/27033921/
dc.relation.ispartofResearch in Veterinary Science
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectColistin resistance
dc.subjectmcr-1
dc.subjectPmrAB
dc.subjectPlasmid
dc.subjectS. enterica
dc.subjectE. coli
dc.titleDetection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli and Salmonella enterica isolated from poultry and swine in Spaineng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage135
oaire.citation.startPage134
oaire.citation.titleResearch in Veterinary Science
oaire.citation.volume105
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
1-s2.0-S0034528816300303-main.pdf
Size:
164.5 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.32 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

MARE - Artigos com peer review
ESTM - Artigos em revistas internacionais