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Valuable compounds in macroalgae extracts
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Advisor(s)
Abstract(s)
Bioactive compounds present in ethanolic extracts from 18 macroalgae of the Portuguese coast were analysed by gas chromatography–mass spectrometry (GC–MS), leading to the characterization of 14 compounds: proline, phloroglucinol, mannitol, 8 fatty acids and 3 sterols. A dose-dependent response
against enzymes with biological significance (a-glucosidase, acetylcholinesterase and butyrylcholinesterase) and free radicals (DPPH, nitric oxide, superoxide and hydroxyl) was found, Phaeophyta being the
most promising group. A PCA analysis was performed and allowed the establishment of a correlation
between the algae chemical composition and the biological activity. Cystoseira tamariscifolia (Hudson)
Papenfuss, Cystoseira nodicaulis (Withering) M. Roberts, Cystoseira usneoides (Linnaeus) M. Roberts and
Fucus spiralis Linnaeus are among the most active species, which is in accordance with their higher contents in phloroglucinol, mannitol, oleic, arachidonic and eicosapentaenoic acids, and fucosterol. The
results point to the potential interest of the use of Phaeophyta species as food additives, due to their
potent antiradical activities, and especially highlights the importance of F. spiralis in the food chain of
Mediterranean countries. Moreover, the incorporation of the extracts of these species in food products,
nutraceutical and pharmaceutical preparations for human health should also be instigated, since they
can suppress hyperglycemia and inhibit cholinesterases.
Description
Keywords
Macroalgae Phloroglucinol Polyols Fatty acids Sterols Bioactivity
Pedagogical Context
Citation
Andrade PB, Barbosa M, Matos RP, Lopes G, Vinholes J, Mouga T, Valentão P (2013). Valuable compounds in macroalgae extracts. Food Chemistry 138 (2,3):1819-1828 (doi.org/10.1016/j.foodchem.2012.11.081)