Laboratory for Integrative and Translational Research in Population Health

Publications

Definitions of determinants of physical activity behaviour: process and outcome of consensus from the DE-PASS expert group

Publication . Dygrýn, Jan; Brazo-Sayavera, Javier; Cruz, Joana; Gebremariam, Mekdes Kebede; Ribeiro, José Carlos; Capranica, Laura; MacDonncha, Ciaran; Netz, Yael

Background Despite extensive research on physical activity behaviour (PAB), consensus is lacking on related terms and definitions, thereby hindering the ability to compare findings between studies and to develop reliable assessment tools. This study therefore aimed to establish consensus on the definitions of key PAB determinants. Methods First, an international expert steering committee was established, comprising members of the European Cooperation in Science and Technology (COST) action “DEterminants of Physical ActivitieS in Settings” (DE‑PASS). Recently published review‑level studies were used to identify key determinants of PAB. Two independent reviewers systematically reviewed the literature to catalogue the range of definitions used for key determinants of PAB (steps 1–2). A two‑round modified Delphi survey was conducted online from February to September 2023, to determine the optimal definition for each determinant. In round 1, experts selected the most suitable definition for each of the 41 initially identified determinants. In round 2, experts ranked the appropriateness of the definition selected from round 1 on a 5‑point Likert scale. Consensus was defined a priori as ≥ 75% agreement on the definition (i.e., ratings of ≥ 4 points). A professional English language expert ensured concise, coherent wording and high‑quality editing of the definitions (steps 3–6). Results Eighty‑five experts in PAB research participated in round 1, and sixty‑nine experts in round 2. Consensus of definitions was achieved for 39 of the 41 determinants (88.4%–98.6% agreement). The consensus threshold was not achieved for two determinants: genetic profile and regulation (69.6%) and backyard access/size (73.9%). Conclusions The findings of this study offer a consensus‑based set of definitions for 39 key determinants of PAB. These definitions can be used homogenously in academic research on physical activity.

2025-03-18Journal article

Open access

Assessment of potentially motivating factors to follow time-restricted eating protocols in a population of adults living in Portugal

Publication . Lages, Marlene; Carmo Silva, Sara; Barros, Renata; Guarino, Maria

Chrononutrition is a growing field that has been attracting significant attention for its potential benefits in metabolic health and body weight regulation. Among chrononutrition strategies, time-restricted eating (TRE) is the most extensively investigated approach in clinical studies. TRE intends to synchronise eating and fasting cycles with the human circadian rhythms. However, larger and longer randomised clinical trials are still needed to establish the effectiveness and long-term health outcomes of TRE interventions. Furthermore, it is crucial to explore whether individuals in free-living conditions, outside controlled clinical settings, can successfully adopt TRE principles into their daily routines to achieve potential health benefits. This study aimed to investigate the association between daily routines and potential adherence to TRE protocols, as well as to identify factors that can potentially predict adherence to these protocols in a sample of adults living in Portugal. A cross-sectional study was conducted using an online questionnaire to assess dietary and sleeping habits, daily routines and the likelihood of adherence to various restrictions in daily eating windows. Associations between variables were analysed using the Spearman correlation coefficient and the Chi-Square test, while an ordinal logistic regression was performed to identify predictive factors. Statistical analyses were conducted on IBM SPSS Statistics version 29.0. The questionnaire was filled out by 130 participants (80 % women) with a mean age of 37.9 ± 13.59 years. On workdays, 71.6 % of participants reported a daily eating window of 12 to 14 h, while on free days, the highest percentage (46.6 %) reported between 10 and 12 h. A significant inverse correlation was observed between willingness to adhere to a TRE protocol based on perceived health benefits and both age (ρ = -0.356, p < 0.001) and sex (ρ = -0.321, p < 0.001). Moderate correlations were also found between the willingness to follow a TRE protocol on workdays (ρ = 0.538) and free days (ρ = 0.598) and the potential health benefits of this type of intervention (p < 0.001). Additionally, sex was associated with potential adherence to the TRE protocol (χ²(2) = 10.644, p = 0.005), with a tendency for men to show lower willingness for adherence. Associations were also identified between body weight management and reducing the eating window by 1 to 2 h (χ²(12) = 24.883, df = 12, p = 0.015) and 2 to 3 h (χ²(12) = 22.367, p = 0.034). Moreover, the perceived importance of income, body weight management and cooking knowledge were significant predictors of the likelihood of adherence to a TRE protocol with a 3 to 4 h restriction in the eating window on workdays (p < 0.005). These results provide valuable insights that should be considered when translating research into clinical practice, specifically in an adult population, as individuals’ willingness and motivation to adopt TRE protocols in free-living conditions are influenced by multiple factors.

2025-12Journal article

Open access