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- Computational technologies in tissue engineeringPublication . Almeida, H. A.; Bártolo, P. J.In last decades, many advances have been made in order to aid the medical community. Numerous computational technologies have been developed and improved the efficiency in diagnostic and treatment of many diseases. Many of the technologies were developed with the main goal of aiding in the research of genetic and viral diseases. Tissue engineering is a multidisciplinary field that requires the combined effort of cell biologists, engineers, material scientists, mathematicians, geneticists, and clinicians toward the development of biological substitutes that restore, maintain, or improve tissue function. The success of this emerging medical domain relies on the current technological advances. This paper presents an overview of the existing computational technologies that have been implemented in tissue engineering and the design of scaffolds for tissue engineering applications. These computational technologies contemplate medical imaging processing, numerical calculations (structural, vascular and topological) and biofabrication techniques necessary for the scaffolds optimum design and production.
- Maximizing the placement of congruent polyhedrain a parallelepiped containerPublication . Gaspar, M. Belbut; Martins-Ferreira, N.Given multiple identical polyhedral objects and a parallelepiped container, how should one place the objects so that the largest number fits inside the container? This simple question is important in many applications, yet the answer is elusive. In fact, we know of no published solution for this very general formulation. Still, in many circumstances, further restrictions apply, resulting in a large number of variations requiring different algorithmic strategies. In this presentation we will further formalize the problem, present some of its many variations, and in particular one that applies to the stereolithographic rapid prototyping technology.
- Optimalmould-part I: Multi-objective optimization to moulds design for injection of polymersPublication . Ramos, Carina; Carreira, P.; Bártolo, Paulo; Alves, NunoThe problem of mould design optimisation for polymer injection is a key issue for both mouldmaking and polymer injection industries. Several computational tools have proposed to address this problem. However they do not cover all aspects related to both mould design and injection moulding process, usually requiring the geometrical configuration of the initial mould solution. This paper presents a novel multi-objective optimisation tool, integrating CAD and CAE tools to optimise mould design parameters and injection moulding process parameters. No initial geometric definition of the mould is required. An industrial case study was considered to validate the proposed approach and the performance of several optimisation algorithms evaluated.
- Preface of the "Symposium on integrated computational tools for advanced manufacturing"Publication . Alves, NunoThe Symposium on Integrated Computational Tools for Advanced Manufacturing, held within 10th International Conference of Numerical Analysis and Applied Mathematics, Kos, Greece, from September 19 to 25, 2012, is a relevant forum for the scientific exchange of multidisciplinary issues related to integrated computational tools for advanced manufacturing. The symposium contains eight reviewed papers, covering important research topics, such as multidisciplinary optimization, numerical modelling, computer-aided design, computer-aided engineering and additive manufacturing technologies.
- Robust STL processing for extrusion-based manufacturingPublication . Gaspar, M.B.; Martins-Ferreira, N.The slicing and tool-path generation are two fundamental processing steps in rapid prototyping/rapid manufacturing (RP/RM), as well as in CAM. Nevertheless, the specific requirements of the diverse RP/RM techniques are not always addressed by existing tools for CAM. We present a set of efficient and robust algorithms for processing STL files in RP/RM.
- Thermo-kinetic curing model for stereolithographic applicationsPublication . Bártolo, PauloA thermal-kinetic model, using the finite element method to study, simulate and optimise stereolithography, is presented in this paper. The model, which is theoretically rigorous and practical in its implementation, describes both the heat transfer effects and the course of the chemical reaction. This model includes the effects of photo-initiator concentration, temperature and light intensity, predicting the diffusion-controlled effects that occur after vitrification, the phenomenon of unimolecular termination and the shrinkage effects. Light intensity values at the resin surface are defined by assuming an appropriated Gaussian intensity distribution. The Beer-Lambert law enables to describe the decrease in light intensity with depth. The non-linear variation of the glass transition temperature with fractional conversion can be determined and consequently the mechanical behaviour of the resin sample predicted.