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- The Effect of Nutritional Intervention in Nutritional Risk Screening on Hospitalised Lung Cancer PatientsPublication . Oliveira, Raquel; Cabrita, Bruno; Cunha, Ângela; Silva, Sónia; Lima, João P. M.; Martins, Diana; Mendes, FernandoBackground: Lung cancer (LC) patients are prone to suffer from malnutrition. Malnutrition negatively affects patients’ response to therapy, increases the incidence of treatment-related side effects, and decreases survival. Early identification of LC patients who are malnourished or at risk of malnutrition can promote recovery and improve prognosis. Objective: This study aimed to assess the risk and nutritional status of lung cancer patients who are hospitalised, as well as to evaluate the impact of nutritional intervention on the risk of malnutrition. Methods: From January 2022 to December 2023, 53 LC patients hospitalised in a pulmonology department had their nutritional risk (initial and final) and nutritional status (initial) assessed. All were selected for nutritional intervention. Nutrition counselling was the first intervention option, along with dietary changes with/without oral nutritional supplements. Results: At the time of hospitalisation, 90.6% of the patients were at nutritional risk, 45.3% were classified as moderately malnourished, and 35.8% were classified as severely underweight. After the hospitalisation, 73.6% were at nutritional risk at the time of discharge, suggesting a statistically significant decrease in the number of patients with nutritional risk. Conclusions: Most LC patients hospitalised presented an altered nutritional status. Our study suggests that a nutritional intervention must be implemented to reduce malnutrition risk, which may impact prognosis. The comprehensive nutritional problems experienced by LC patients require nutritional assessment and improved individually tailored nutritional support.
- Entre História e silêncio: a surdez de D. João VI e sua ausência nas narrativas educacionaisPublication . Oliveira, Alessandra Furtado de; Ramos, Jacqueline De Faria Barros; Sousa, Célia Maria; Braz, Ruth Maria MarianiA História é uma disciplina acadêmica e uma ferramenta cultural que desempenha papel fundamental na formação das memórias e identidades das sociedades. Assim, neste artigo objetivamos denunciar o processo de apagamento da pessoa com deficiência nos livros didáticos, na figura de D. João VI, que era surdo. A pesquisa tem abordagem qualitativa, foco documental, análise de conteúdo em plataformas de dados e revisão bibliográfica de forma narrativa. Os dados coletados demonstram que o tema da surdez de D. João VI é pouco abordado; quando mencionado, o é muitas vezes de forma superficial, o que contribui para a perpetuação de estereótipos e preconceitos em relação às pessoas com deficiência, além de reforçar a invisibilidade de suas contribuições históricas. Destaca-se a importância da conscientização sobre a diversidade e a necessidade de superar o apagamento das pessoas com deficiência, valorizando sua participação e contribuição para a sociedade.
- Using Secure Multi-Party Computation to Create Clinical Trial CohortsPublication . Borges, Rafael; Ferreira, Bruno; Antunes, Carlos Machado; Maximiano, Marisa; Gomes, Ricardo; Távora, Vitor; Dias, Manuel; Bezerra, Ricardo Correia; Domingues, Patrício; Antunes, Carlos MachadoThe increasing volume of digital medical data offers substantial research opportunities, though its complete utilization is hindered by ongoing privacy and security obstacles. This proof-of-concept study explores and confirms the viability of using Secure Multi-Party Computation (SMPC) to ensure protection and integrity of sensitive patient data, allowing the construction of clinical trial cohorts. Our findings reveal that SMPC facilitates collaborative data analysis on distributed, private datasets with negligible computational costs and optimized data partition sizes. The established architecture incorporates patient information via a blockchain-based decentralized healthcare platform and employs the MPyC library in Python for secure computations on Fast Healthcare Interoperability Resources (FHIR)-format data. The outcomes affirm SMPC’s capacity to maintain patient privacy during cohort formation, with minimal overhead. It illustrates the potential of SMPC-based methodologies to expand access to medical research data. A key contribution of this work is eliminating the need for complex cryptographic key management while maintaining patient privacy, illustrating the potential of SMPC-based methodologies to expand access to medical research data by reducing implementation barriers.
- Pre- and Postharvest Determinants, Technological Innovations and By-Product Valorization in Berry Crops: A Comprehensive and Critical ReviewPublication . Gonçalves, Elsa M.; Ganhão, Rui; Pinheiro, JoaquinaBerries—including strawberries, blueberries, raspberries, blackberries, cranberries, and several less commonly cultivated berry species—are highly valued for their sensory quality and rich content of bioactive compounds, yet they are among the most perishable horticultural products. Their soft texture, high respiration rate, and susceptibility to fungal pathogens lead to rapid postharvest deterioration and significant economic losses. This review synthesizes advances in berry postharvest management reported between 2010 and 2025. Conventional strategies such as rapid precooling, cold-chain optimization, controlled and modified atmospheres, and edible coatings are discussed alongside emerging non-thermal technologies, including UV-C light, ozone, cold plasma, ultrasound, biocontrol agents, and intelligent packaging systems. Particular emphasis is placed on the instability of anthocyanins and other phenolic compounds, microbial spoilage dynamics, and the influence of cultivar genetics and preharvest factors on postharvest performance. The review also highlights opportunities for circular-economy applications, as berry pomace, seeds, and skins represent valuable sources of polyphenols, dietary fiber, and seed oils for use in food, nutraceutical, cosmetic, and bio-based packaging sectors. Looking ahead, future research should prioritize integrated, multi-hurdle, low-residue postharvest strategies, the scale-up of non-thermal technologies, and data-driven cold-chain management. Overall, coordinated physiological, technological, and sustainability-oriented approaches are essential to maintain berry quality, reduce postharvest losses, and strengthen the resilience of berry value chains.