Percorrer por autor "Veiga, Anabela"
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- Continuous production of highly tuned silk/calcium-based composites: exploring new pathways for skin regenerationPublication . Veiga, Anabela; Magalhaes, Rui; Duarte, Marta M.; Dias, Juliana R.; Alves, Nuno M.; Costa-Pinto, Ana Rita; Castro, Filipa; Rocha, Fernando; Oliveira, Ana L.Calcium plays an important role in barrier function repair and skin homeostasis. In particular, calcium phosphates (CaPs) are well established materials for biomedical engineering due to their biocompatibility. To generate biomaterials with a more complete set of biological properties, previously discarded silk sericin (SS) has been recovered and used as a template to grow CaPs. Crucial characteristics for skin applications, such as antibacterial activity, can be further enhanced by doping CaPs with cerium (Ce) ions. The effectiveness of cell attachment and growth on the materials highly depends on their morphology, particle size distribution, and chemical composition. These characteristics can be tailored through the application of oscillatory flow technology, which provides precise mixing control of the reaction medium. Thus, in the present work, CaP/SS and CaP/SS/Ce particles were fabricated for the first time using a modular oscillatory flow plate reactor (MOFPR) in a continuous mode. Furthermore, the biological behavior of both these composites and of previously produced pure CaPs was assessed using human dermal fibroblasts (HDFs). It was demonstrated that both CaP based with plate-shaped nanoparticles and CaP-SS-based composites significantly improved cell viability and proliferation over time. The results obtained represent a first step towards the reinvention of CaPs for skin engineering.
- Diapir Mudstone Properties, Leiria, PortugalPublication . Veiga, Anabela; Quinta-Ferreira, MárioThe engineering geology study of the Dagorda Formation outcropping in the core of the Parceiros-Leiria diapir, was based on field reconnaissance, on in situ and laboratory tests. The formation is constituted mainly by clay and silt, sometimes with sand, occasionally with gypsum or marls. The engineering geology properties of the fine materials showed large variability depending on their degree of consolidation and water content, ranging from very poor to fair. The presence of soluble minerals can develop dissolution voids. When exposed, for example in excavation surfaces, they tend to deteriorate because of decompression and exposure to the external environment, easily losing strength when wet, which facilitates the failure on slopes or foundations. The presence of soluble minerals (gypsum and rock salt at greater depth) can develop dissolution voids due to circulating water. In depth the variation of the mechanical properties may lead to difficulties in foundation ground, as well as difficulty of concreting piles, due to the escape of concrete between neighboring piles along fissures and dissolution voids. The occurrence of very low strength seams, may constrain the stability of cuttings. The unusual geotechnical behavior of these terrains due to the presence of both clay and soluble minerals must be taken into account. In all engineering works to be carried out on these materials it is recommended to develop a detailed engineering geology study prior to construction, in order to early identify the problems and to define the suitable solutions and construction techniques to be adapted to each case. The construction works must have geotechnical assistance in order to improve the construction operations.
- Geostatistical analysis of settlements induced by liquefaction: case study river Lis Alluviums, PortugalPublication . Veiga, Anabela; Mourato, Sandra; Rodrigues, HugoIn the present work the result of the application of geostatistical methods to soil settlement data is presented. The settlements are induced by liquefaction as a result of an earthquake of magnitude 5.5. In the present paper the ArcGIS Geostatistical Analyst software was used, where a number of Kriging methods are available. Geostatistical analysis was performed on two phases: (i) modelling the semivariogram to analyse the surface properties and; (ii) application of a Kriging method. The best adjustment was obtained with a Gaussian model with a first order function trend removal. The settlement values were obtained from the analysis and treatment of results of SPT tests carried out on soils corresponding to alluvial soils in the urban centre of Leiria, Portugal. The results show a significant area where are expected large settlements that can generate significant damages in the building stock and infrastructures.
- The Use of New Learning Technologies in Higher Education Classroom: A Case StudyPublication . Esteves, Micaela Dinis; Pereira, Angela; Veiga, Nuno; Vasco, Rui; Veiga, AnabelaWe have conducted a study with higher level education students, in lecture classes of three Undergraduate Courses and one Professional Higher Technical Course that involved six different subjects with a total of 324 students. In this research the use of Game-Based Learning platform was analysed in order to encourage the students’ participation, increasing motivation and keeping them motivated and committed during lessons, therefore, increasing their learning skills. Based on these results, we recommend that Kahoot is used in lectures in order to help students develop their performances and abilities and at the same time be more successful and prepared to have an active participation in society.