Percorrer por autor "Mitsuishi, Mamoru"
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- BiomanufacturingPublication . Mitsuishi, Mamoru; Cao, Jian; Bártolo, Paulo; Friedrich, Dirk; Shih, Albert J.; Rajurkar, Kamlakar; Sugita, Naohiko; Harada, KanakoBiomedical markets are large and rapidly growing owing to increasing demand for better healthcare services. The development of innovative biomedical systems can produce major breakthroughs in the healthcare industry, and advanced manufacturing technologies can propel such innovations. This paper summarises the field of biomanufacturing: namely, biospecific design constraints, biomechatronics, biofabrication, biodesign, and assembly. This paper presents state-of-the-art research, current problems, and future goals while providing fundamental knowledge required for entry into the biomedical industry. Biomanufacturing provides excellent opportunities for multi-disciplinary collaborations, both in academia and industry, and can lead to further advances in many engineering fields.
- Biomedical production of implants by additive electro-chemical and physical processesPublication . Bartolo, Paulo; Kruth, Jean-Pierre; Silva, Jorge; Levy, Gideon; Malshe, Ajay; Rajurkar, Kamlakar; Mitsuishi, Mamoru; Ciurana, Joaquim; Leu, MingBiomanufacturing integrates life science and engineering fundamentals to produce biocompatible products enhancing the quality of life. The state-of-the-art of this rapidly evolving manufacturing sector is presented and discussed, in particular the additive electrical, chemical and physical processes currently being applied to produce synthetic and biological parts. This fabrication strategy is strongly materialdependent, so the main classes of biomaterials are detailed. It is explained the potential to process composite materials combining synthetic and biological materials, such as cells, proteins and growth factors, as well the interdependences between materials and processes. The techniques commonly used to increase the bioactivity of clinical implants and improve the interface characteristics between biological tissues and implants are also presented.