Percorrer por autor "Melchels, F."
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- Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine fusion modelPublication . Yong, M.; Melchels, F.; Vaquette, C.; Hutmacher, D.; Adam, C.; Domingos, M.; Bártolo, P.We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recombinant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.