Percorrer por autor "Almeida, Henrique de Amorim"
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- Anthropometrics and Ergonomics in Pregnant WomenPublication . Almeida, Henrique de Amorim; Teixeira Ascenso, Rita Margarida; Oliveira, EunicePregnancy is a women life event that impacts her own and offspring’s life; surprisingly, few systematic and scientific maternal information is available in the literature for anthropometric and ergonomic purposes. Regarding ergonomics, some authors state that guidelines should be design for pregnant women. These guidelines may consider anthropometric issues such as changes in weight and distribution of mass, which influence mobility, home and labour performance, mood and cognition. Anthropometrics allows the body measurement, but in pregnancy women are sparingly characterized, besides Body Mass Index and few other parameters. Ergonomics not only aids in the design process of work or home layouts, but also contains several evaluation tools to determine the level of risk of musculoskeletal disorders of daily or labour tasks. Some of these tools are very specific and others have certain conditions that should be met before using them. The purpose of this study is to present an overview of guidelines and discuss which anthropometric and ergonomic evaluation tools may be used, and under which conditions can be implemented in pregnant women.
- Biofabrication and the Medical Field: Which is the scenario for 2030?Publication . Serrano, Emanuel S.; Vitorino, Liliana Coutinho; Almeida, Henrique de Amorim
- Biomanufacturing for tissue engineering: Present and future trendsPublication . Bartolo, Paulo; Chua, C. K.; Almeida, Henrique de Amorim; Chou, S. M.; Lim, A. S. C.Tissue engineering, often referred to as regenerative medicine and reparative medicine, is an interdisciplinary field that necessitates the combined effort of cell biologists, engineers, material scientists, mathematicians, geneticists, and clinicians toward the development of biological substitutes that restore, maintain, or improve tissue function. It has emerged as a rapidly expanding approach to address the organ shortage problem and comprises tissue regeneration and organ substitution. Cells placed on/or within constructs is the most common strategy in tissue engineering. Successful cell seeding depends on fast attachment of cell to scaffolds, high cell survival and uniform cell distribution. The seeding time is strongly dependent on the scaffold material and architecture. Scaffolds provide an initial biochemical substrate for the novel tissue until cells can produce their own extra-cellular matrix (ECM). Thus scaffolds not only define the 3D space for the formation of new tissues, but also serve to provide tissues with appropriate functions. These scaffolds are often critical, both in vivo (within the body) or in vitro (outside the body) mimicking in vivo conditions. Additive fabrication processes represent a new group of non-conventional fabrication techniques recently introduced in the biomedical engineering field. In tissue engineering, additive fabrication processes have been used to produce scaffolds with customised external shape and predefined internal morphology, allowing good control of pore size and pore distribution. This article provides a comprehensive state-of-the-art review of the application of biomanufacturing additive processes in the field of tissue engineering. New and moving trends in biomanufacturing technologies and the concept of direct cell-printing technologies are also discussed.
- Medical devices: from design to productionPublication . Almeida, Henrique de Amorim; Ruben, Rui B.
- Numerical Calculations in Tissue EngineeringPublication . Almeida, Henrique de Amorim; Bártolo, Paulo J.The design of optimized scaffolds for tissue engineering is a key topic of research, as the complex macro- and micro- architectures required for a scaffold depends not only on the mechanical properties, but also on the physical and molecular queues of the surrounding tissue within the defect site. Thus, the prediction of optimal features for tissue engineering scaffolds is very important for its mechanical, vascular or topological properties. The relationship between high scaffold porosity and high mechanical properties is contradictory, as it becomes even more complex due to the scaffold degradation process. A scaffold design strategy was developed, based on the finite element method, to optimise the scaffold design regarding the mechanical and vascular properties as a function of porosity. Scaffolds can be considered as a LEGO structure formed by an association of small elementary units or blocks. In this research work, two types of family elementary scaffold units were considered: non-triple periodic minimal surfaces and triple periodic minimal surfaces that describe natural existing surfaces. The main objective of this work is to present the undergoing research based on numerical simulations for the evaluation and prediction of the scaffold's behaviour under structural and vascular loading, and its topological optimisation.
- The Role of Ultrasound Imaging of Musculotendinous Structures in the Elderly PopulationPublication . Carrão, Luis Miguel Costa; Santos, Rute; Espanha, Margarida; Armada-da-Silva, Paulo; Amaral, Ana; Amado, Sandra; Almeida, Henrique de Amorim; Pascoal-Faria, Paula; Veloso, AntónioUltrasound (US) is a noninvasive and real-time method that allows the evaluating muscles and tendons. The enhanced echo-intensity (EI) on ultrasonography images of skeletal muscle is believed to reflect changes in muscle quality (MQ), and these changes accompany aging. Also related to aging, and that may more severely affect women than men, is the well-known loss of skeletal muscle mass. Often associated with the accumulation of connective tissues (e.g., adipose), it affects muscle strength and MQ and causes functional impairment. This chapter demonstrates the potential use of US imaging for assessing muscle changes associated with aging and functional decline.
- A study of 4D printing and functionally graded additive manufacturingPublication . Pei, Eujin; Loh, Giselle Hsiang; Harrison, David; Almeida, Henrique de Amorim; Verona, Mario Domingo Monzón; Paz, RubénThe purpose of this paper is to clarify the concept of Functionally Graded Additive Manufacturing and 4D printing. We defined that Functionally Graded Additive Manufacturing (FGAM) is a single AM process that includes the gradationally mixing of materials to fabricate freeform geometries with variable-properties within one component. This should not be used interchangeably with the term 4D Printing in which refers to the use of smart materials in Additive Manufacturing to produce parts that have the ability to change when exposed to an environmental stimuli. In this paper, we highlight that FGAM requires better computational tools for modelling, simulation and fabrication as current CAD systems are incapable of supporting the complex workflow, suggesting that future work should focus on aspects of material characterization and better control processes.
- Thermal analysis of an extrusion system of a 3-D bioprinterPublication . Ribeiro G.S.; Silva J.V.L.; Freitas D.; Bartolo P.; Almeida, Henrique de Amorim; Silveira Z.C.This work presents a finite element thermal analysis of a 3-D bioprinter desktop based on Fused Deposition Modeling (FDM) with applications on tissue engineering, designed by the Centre for Rapid and Sustainable Product Development - Leiria, Portugal. The purpose of this work it is compare three possibilities of temperature control of the machine during the extrusion process, considering the use of a biodegradable polyester (Polycaprolactone - PCL) as raw material. The first two configurations simulate approaches typically adopted in an attempt to keep the polymer as close as possible to 80 °C and prevent its premature solidification at a critical point. The third configuration considers a hypothetical material substitution to enhance thermal conductivity. The results indicate that the first two configurations are not sufficient to achieve total control of the polymer temperature. However, the third configuration show a significant potential to improve the thermal control of the extrusion process.