CDRsp - Comunicações em conferências internacionais
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Browsing CDRsp - Comunicações em conferências internacionais by Author "Almeida, Henrique de Amorim"
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- Numerical Calculations in Tissue EngineeringPublication . Almeida, Henrique de Amorim; Bártolo, Paulo J.The design of optimized scaffolds for tissue engineering is a key topic of research, as the complex macro- and micro- architectures required for a scaffold depends not only on the mechanical properties, but also on the physical and molecular queues of the surrounding tissue within the defect site. Thus, the prediction of optimal features for tissue engineering scaffolds is very important for its mechanical, vascular or topological properties. The relationship between high scaffold porosity and high mechanical properties is contradictory, as it becomes even more complex due to the scaffold degradation process. A scaffold design strategy was developed, based on the finite element method, to optimise the scaffold design regarding the mechanical and vascular properties as a function of porosity. Scaffolds can be considered as a LEGO structure formed by an association of small elementary units or blocks. In this research work, two types of family elementary scaffold units were considered: non-triple periodic minimal surfaces and triple periodic minimal surfaces that describe natural existing surfaces. The main objective of this work is to present the undergoing research based on numerical simulations for the evaluation and prediction of the scaffold's behaviour under structural and vascular loading, and its topological optimisation.
- Thermal analysis of an extrusion system of a 3-D bioprinterPublication . Ribeiro G.S.; Silva J.V.L.; Freitas D.; Bartolo P.; Almeida, Henrique de Amorim; Silveira Z.C.This work presents a finite element thermal analysis of a 3-D bioprinter desktop based on Fused Deposition Modeling (FDM) with applications on tissue engineering, designed by the Centre for Rapid and Sustainable Product Development - Leiria, Portugal. The purpose of this work it is compare three possibilities of temperature control of the machine during the extrusion process, considering the use of a biodegradable polyester (Polycaprolactone - PCL) as raw material. The first two configurations simulate approaches typically adopted in an attempt to keep the polymer as close as possible to 80 °C and prevent its premature solidification at a critical point. The third configuration considers a hypothetical material substitution to enhance thermal conductivity. The results indicate that the first two configurations are not sufficient to achieve total control of the polymer temperature. However, the third configuration show a significant potential to improve the thermal control of the extrusion process.