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PCL Scaffolds with Collagen Bioactivator for Applications in Tissue Engineering

2013Comunicação em conferência Acesso aberto
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datacite.subject.fosEngenharia e Tecnologia::Biotecnologia Industrial
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorSousa, Inês
dc.contributor.authorMendes, Ausenda
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2026-03-20T10:13:41Z
dc.date.available2026-03-20T10:13:41Z
dc.date.issued2013
dc.description.abstractThe need for human tissues is fundament in certain genetic diseases or accidents of everyday life, they are a primary source for public health. In recent years, to alleviate these effects there was an improvement in the development of tissue engineering, scaffolds or matrices, to support an adequate mechanical and biological environment necessary for the regeneration of damaged tissues. These scaffolds are structures allowing adhesion, differentiation, cell proliferation and the supply of nutrients for growing cells. This paper aims to obtain PCL scaffolds bioactivators, to use as support matrices for the development of human tissues, as PCL is a biomaterial widely used in the biomedical field, due to its biocompatibility, mechanical strength and biodegradability. However, this biomaterial is hydrophobic, which means that there are difficulties in cell adhesion. To solve this problem, a coating of PCL scaffolds with collagen was used, since collagen is a hydrophilic protein existing in the formation of various tissues, so improves cell adhesion.eng
dc.description.sponsorshipThis research was supported by the Portuguese Foundation for Science and Technology through the strategic project Pest-OE/EME/UI4044/2011.
dc.identifier.citationInês Sousa, Ausenda Mendes, Paulo J. Bártolo, PCL Scaffolds with Collagen Bioactivator for Applications in Tissue Engineering, Procedia Engineering, Volume 59, 2013, Pages 279-284, ISSN 1877-7058, https://doi.org/10.1016/j.proeng.2013.05.122.
dc.identifier.doi10.1016/j.proeng.2013.05.122
dc.identifier.issn1877-7058
dc.identifier.urihttp://hdl.handle.net/10400.8/15935
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S1877705813010369?via%3Dihub
dc.relation.ispartofProcedia Engineering
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectBiocompatibility
dc.subjectCollagen
dc.subjectPoly(ɛ-caprolactona)
dc.subjectScaffolds
dc.subjectTissue Engineering
dc.titlePCL Scaffolds with Collagen Bioactivator for Applications in Tissue Engineering
dc.typeconference paper
dspace.entity.typePublication
oaire.awardNumberPEst-OE/EME/UI4044/2011
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.conferenceDate2013
oaire.citation.endPage284
oaire.citation.startPage279
oaire.citation.titleProcedia Engineering
oaire.citation.volume59
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.affiliation.nameCDRSP
person.familyNameSousa
person.familyNameMendes
person.familyNameBartolo
person.givenNameInês
person.givenNameAusenda
person.givenNamePaulo
person.identifier203086
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0001-7987-1033
person.identifier.orcid0000-0003-3004-8972
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id7102443940
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationb3a5d8f4-3554-429f-8776-21b60a765f39
relation.isAuthorOfPublication5ac3b700-95c6-4782-861a-deea8e449a7c
relation.isAuthorOfPublicationab44d1ae-46d0-45c2-b19f-200024b5a990
relation.isAuthorOfPublication.latestForDiscovery5ac3b700-95c6-4782-861a-deea8e449a7c
relation.isProjectOfPublication44bd1c93-9ee1-4685-a408-c2baa61ffbcd
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