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What names for covert awareness? A systematic review

dc.contributor.authorSchnakers, Caroline
dc.contributor.authorBauer, Chase
dc.contributor.authorFormisano, Rita
dc.contributor.authorNoé, Enrique
dc.contributor.authorLlorens, Roberto
dc.contributor.authorLejeune, Nicolas
dc.contributor.authorFarisco, Michele
dc.contributor.authorTeixeira, Liliana
dc.contributor.authorMorrissey, Ann-Marie
dc.contributor.authorDe Marco, Sabrina
dc.contributor.authorVeeramuthu, Vigneswaran
dc.contributor.authorIlina, Kseniya
dc.contributor.authorEdlow, Brian L.
dc.contributor.authorGosseries, Olivia
dc.contributor.authorZandalasini, Matteo
dc.contributor.authorDe Bellis, Francesco
dc.contributor.authorThibaut, Aurore
dc.contributor.authorEstraneo, Anna
dc.date.accessioned2023-05-23T14:31:19Z
dc.date.available2023-05-23T14:31:19Z
dc.date.issued2022-08-05
dc.descriptionFunding: MF was supported by the European Union’s Horizon 2020 Framework Programme for Research and Innovation under the Specific Grant Agreement (No. 945539) (Human Brain Project SGA3).pt_PT
dc.description.abstractAfter a severe brain injury, some patients do not fully recover consciousness and remain in a prolonged Disorder of Consciousness (DoC) such as the vegetative state/unresponsive wakefulness syndrome (VS/UWS) or the minimally conscious state (MCS). Patients in a VS/UWS open their eyes and present preserved autonomic functions, but they are not conscious and show only reflexive behaviors while the MCS is being characterized by the presence of inconsistent but clearly discernible behavioral signs of consciousness (e.g., visual tracking, command following) (The Multi-Society Task Force on Persistent Vegetative State, 1994; Giacino et al., 2002). More recently, the MCS has been subdivided in two clinical entities, MCS+ and MCS– (characterized by the presence/absence of command-following, intelligible verbalization, and intentional communication) supported by metabolic differences in areas associated with both consciousness and language (e.g., lower metabolism in the precuneus and thalamus and in the left middle temporal cortex in MCS-) (Thibaut et al., 2020). Prolonged DoCs are a relatively rare condition (estimated prevalence of 5,000–42,000 and 112,000–280,000 for VS/UWS and MCS, respectively, in the US) implying severe disability and complete dependence, which can last from 28 days to decades (Giacino et al., 2018)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSchnakers C, Bauer C, Formisano R, Noé E, Llorens R, Lejeune N, Farisco M, Teixeira L, Morrissey AM, De Marco S, Veeramuthu V, Ilina K, Edlow BL, Gosseries O, Zandalasini M, De Bellis F, Thibaut A, Estraneo A. What names for covert awareness? A systematic review. Front Hum Neurosci. 2022 Aug 5;16:971315. doi: 10.3389/fnhum.2022.971315. PMID: 35992948; PMCID: PMC9389234.pt_PT
dc.identifier.doihttps://doi.org/10.3389/fnhum.2022.971315pt_PT
dc.identifier.eissn1662-5161
dc.identifier.other971315
dc.identifier.pmc9389234
dc.identifier.pmid35992948
dc.identifier.urihttp://hdl.handle.net/10400.8/8501
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontiers Mediapt_PT
dc.relationHuman Brain Project Specific Grant Agreement 3
dc.relation.publisherversionhttps://www.frontiersin.org/articles/10.3389/fnhum.2022.971315/fullpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectVegetative statept_PT
dc.subjectUnresponsive wakefulness syndromept_PT
dc.subjectMinimally conscious statept_PT
dc.subjectCovert awarenesspt_PT
dc.subjectCognitive motor dissociationpt_PT
dc.subjectFunctional locked-inpt_PT
dc.subjectNon-behavioralpt_PT
dc.subjectMCSpt_PT
dc.subjectConsciousnespt_PT
dc.titleWhat names for covert awareness? A systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHuman Brain Project Specific Grant Agreement 3
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/945539/EU
oaire.citation.titleFrontiers in Human Neurosciencept_PT
oaire.citation.volume16pt_PT
oaire.fundingStreamH2020
person.familyNameda Conceição Teixeira
person.givenNameLiliana
person.identifier1298780
person.identifier.ciencia-id9811-DD3D-DD0F
person.identifier.orcid0000-0001-9408-859X
person.identifier.ridAAD-8708-2019
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationb949135a-bbec-4770-8d74-502c0ba04029
relation.isAuthorOfPublication.latestForDiscoveryb949135a-bbec-4770-8d74-502c0ba04029
relation.isProjectOfPublication67e37ff3-adca-4015-b3f9-52449ea890ae
relation.isProjectOfPublication.latestForDiscovery67e37ff3-adca-4015-b3f9-52449ea890ae

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