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Tensile and Shear Stress Evaluation of Schwartz Surfaces for Scaffold Design
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Orientador(es)
Resumo(s)
Tissue engineering represents a new, emerging interdisciplinary field involving combined efforts of several scientific domains towards the development of biological substitutes to restore, maintain, or improve tissue functions. Scaffolds provide a temporary mechanical and vascular support for tissue regeneration while shaping the in-growth tissues. These scaffolds must be biocompatible, biodegradable, with appropriate porosity, pore structure and pore distribution and optimal structural and vascular performance, having both surface and structural compatibility. Surface compatibility means a chemical, biological and physical suitability to the host tissue. Structural compatibility corresponds to an optimal adaptation to the mechanical behaviour of the host tissue. The design of optimised scaffolds based on the fundamental knowledge of its macro microstructure is a relevant topic of research. This research proposes the use of geometric structures based on Triple Periodic Minimal Surfaces, namely, Schwartz geometries for tensile and shear stress applications. Geometries based on these surfaces enables the design of vary high surface-to-volume ratio structures with high porosity and mechanical/vascular properties. Numerical simulations on the Schwartz surfaces were performed considering two geometric variations: surface thickness and surface radius construction. The results demonstrate how the mechanical (Elastic and Shear) cell stimuli vary with the geometric variations of the Schwartz surfaces.
Descrição
Conference name
4th International Conference on Tissue Engineering - An ECCOMAS Thematic Conference, ICTE 2015
Conference date 25 June 2015 - 27 June 2015
Conference city Lisboa, Portugal
Conference date 25 June 2015 - 27 June 2015
Conference city Lisboa, Portugal
Palavras-chave
Numerical simulation Scaffolds Schwartz surfaces Structural analysis Tissue engineering
Contexto Educativo
Citação
Henrique A. Almeida, Paulo J. Bártolo, Tensile and Shear Stress Evaluation of Schwartz Surfaces for Scaffold Design, Procedia Engineering, Volume 110, 2015, Pages 167-174, ISSN 1877-7058, https://doi.org/10.1016/j.proeng.2015.07.025.
Editora
Elsevier