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Feasibility of focal transcranial DC polarization with simultaneous EEG recording: preliminary assessment in healthy subjects and human epilepsy

2012-11Journal article Restricted access
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dc.contributor.authorFaria, Paula
dc.contributor.authorFregni, Felipe
dc.contributor.authorSebastião, Fernando
dc.contributor.authorDias, Ana I.
dc.contributor.authorLeal, Alberto
dc.date.accessioned2012-11-19T15:17:08Z
dc.date.available2012-11-19T15:17:08Z
dc.date.issued2012-11
dc.descriptionArtigo em acesso restrito. Apenas está disponível o abstract.por
dc.description.abstractWe aimed to investigate the feasibility of an experimental system for simultaneous transcranial DC stimulation (tDCS) and EEG recording in human epilepsy. We report tolerability of this system in a cross-over controlled trial with 15 healthy subjects and preliminary effects of its use, testing repeated tDCS sessions, in two patients with drug-refractory Continuous Spike-Wave Discharges During Slow Sleep (CSWS). Our system combining continuous recording of the EEG with tDCS allows detailed evaluation of the interictal activity during the entire process. Stimulation with 1mA was well-tolerated in both healthy volunteers and patients with refractory epilepsy. The large reduction in interictal epileptiform EEG discharges in the two subjects with epilepsy supports further investigation of tDCS using this combined method of stimulation and monitoring in epilepsy. Continuous monitoring of epileptic activity throughout tDCS improves safety and allows detailed evaluation of epileptic activity changes induced by tDCS in patients.por
dc.description.sponsorshipFCT (Fundação para a Ciência e a Tecnologia); CIMIT (Center for Integration of Medicine and Innovative Technology); Tecnifar SA.por
dc.identifier.citationFaria, P., Fregni, F., Sebastião, F., Dias, A. I. e Leal, A. (2012). Feasibility of focal transcranial DC polarization with simultaneous EEG recording: Preliminary assessment in healthy subjects and human epilepsy, Epilepsy & Behavior, 25(3), 417-425.por
dc.identifier.issn1525-5050
dc.identifier.urihttp://hdl.handle.net/10400.8/674
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectEEGpor
dc.subjecttDCSpor
dc.subjectPolarizationpor
dc.subjectEpilepsypor
dc.subjectTranscranialpor
dc.subjectSafetypor
dc.titleFeasibility of focal transcranial DC polarization with simultaneous EEG recording: preliminary assessment in healthy subjects and human epilepsypor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBoston, USApor
oaire.citation.endPage425por
oaire.citation.startPage417por
oaire.citation.titleEpilepsy & Behaviorpor
person.familyNameSebastião
person.givenNameFernando
person.identifier.ciencia-id7717-1FCA-3D56
person.identifier.orcid0000-0002-8792-4649
person.identifier.scopus-author-id55469915200
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication3148059a-b62e-4a9c-8a34-a7b0733545da
relation.isAuthorOfPublication.latestForDiscovery3148059a-b62e-4a9c-8a34-a7b0733545da

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