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Degradation Behavior of Biopolymer-based Membranes for Skin Tissue Regeneration

2013Artigo científico Acesso aberto
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datacite.subject.fosEngenharia e Tecnologia::Engenharia dos Materiais
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorPereira, Rúben F.
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2026-03-20T09:34:11Z
dc.date.available2026-03-20T09:34:11Z
dc.date.issued2013
dc.description.abstractThis research work investigates the long term in vitro degradation behavior of alginate-aloe vera composite membranes for skin regeneration. The membranes were prepared through a two-step procedure, which involves the synthesis of thin membranes and the crosslinking reaction. Degradation tests were performed through the immersion of the membranes into simulated body fluid solution at pH 7.4 and physiological temperature, during 6 months. Alginate-aloe vera membranes are resistant to the hydrolytic degradation and exhibit weight loss values in a range of 20.37-26.32%. Results show that an increase in the aloe vera content leads to a slight increase in the weight loss during the degradation process. Preliminary drug release studies, using nitrofurazone as a model drug, suggest the ability of the developed membranes to be used as a drug delivery system.eng
dc.description.sponsorshipThis work was supported by the Portuguese Foundation for Science and Technology through the strategic project Pest-OE/EME/UI4044/2011. The authors would like to thank ZeusQuímica Lda and Aloecorp Inc. for kindly supplying the aloe vera.
dc.identifier.citationRúben F. Pereira, Paulo J. Bártolo, Degradation Behavior of Biopolymer-based Membranes for Skin Tissue Regeneration, Procedia Engineering, Volume 59, 2013, Pages 285-291, ISSN 1877-7058, https://doi.org/10.1016/j.proeng.2013.05.123.
dc.identifier.doi10.1016/j.proeng.2013.05.123
dc.identifier.issn1877-7058
dc.identifier.urihttp://hdl.handle.net/10400.8/15933
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S1877705813010370?via%3Dihub
dc.relation.ispartofProcedia Engineering
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectDegradation
dc.subjectAlginate
dc.subjectAloe vera
dc.subjectMembrane
dc.subjectSkin
dc.titleDegradation Behavior of Biopolymer-based Membranes for Skin Tissue Regenerationeng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberPEst-OE/EME/UI4044/2011
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.endPage291
oaire.citation.startPage285
oaire.citation.titleProcedia Engineering
oaire.citation.volume59
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameBrás Pereira
person.familyNameBartolo
person.givenNameRúben Filipe
person.givenNamePaulo
person.identifier1337969
person.identifier203086
person.identifier.ciencia-id9417-153E-4473
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-7255-3400
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridP-8503-2018
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55421048100
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationeda35774-59b3-4801-aa88-9c20f4c31a78
relation.isAuthorOfPublicationab44d1ae-46d0-45c2-b19f-200024b5a990
relation.isAuthorOfPublication.latestForDiscoveryeda35774-59b3-4801-aa88-9c20f4c31a78
relation.isProjectOfPublication44bd1c93-9ee1-4685-a408-c2baa61ffbcd
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