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Sea cucumber Holothuria forskali, a new resource for aquaculture? Reproductive biology and nutraceutical approach

2015Artigo científico Acesso aberto
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dc.contributor.authorSantos, Rita
dc.contributor.authorDias, Simaura
dc.contributor.authorPinteus, Susete
dc.contributor.authorSilva, Joana
dc.contributor.authorAlves, Celso
dc.contributor.authorTecelão, Carla
dc.contributor.authorPedrosa, Rui
dc.contributor.authorPombo, Ana
dc.date.accessioned2021-08-12T13:28:22Z
dc.date.available2021-08-12T13:28:22Z
dc.date.issued2015
dc.description.abstractSea cucumbers are highly marketable as a food product due to their nutritional value. Also, it has been suggested that sea cucumbers possess a wide range of bioactive compounds that can be used in the pharmaceutical industry. In this study, the reproductive biology of Holothuria forskali was performed by evaluating the gonadosomatic index (GI) and histological analyses of the gonadal tubules. The biotechnological potential was assessed through the evaluation of the antioxidant, antimicrobial and antitumor potential. Finally, the fatty acid profile was also evaluated. These three subjects were chosen to increase the interest and to focus the economic potential of this species rearing, predicting that it can be sold in Europe or export to Asia to be used for human consumption or for the pharmaceutical industry. The GI and the histological analysis of the gonadal tubules revealed that the range from February to March corresponds to the peak of gonads maturation. Furthermore, the methanolic fraction revealed the highest antimicrobial potential against Candida albicans with an IC50 of 233.2 mg mL -1. Also, this fraction presented the highest cytotoxic and anti-proliferative activities through the method for measuring cell proliferation method in both cell lines, with an IC50 of 238.2 and 396.0 mg mL -1 for MCF-7 cells respectively and 260.3 and 218.7 mg mL -1 for HepG-2 cells respectively. Regarding the fatty acid profile, the total fat content was 4.83% and the highest values were obtained for palmitic acid (9.96%), stearic acid (11.23%), eicosapentaenoic acid (10.49%) and arachidonic acid (20.36%).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1111/are.12683pt_PT
dc.identifier.issn1355-557X
dc.identifier.issn1365-2109
dc.identifier.urihttp://hdl.handle.net/10400.8/6087
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/abs/10.1111/are.12683pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSea cucumberpt_PT
dc.subjectAntimicrobial activitypt_PT
dc.subjectAntitumor activitypt_PT
dc.subjectHepG-2 and MCF-7 cell linespt_PT
dc.subjectMarine natural compoundspt_PT
dc.subjectFatty acid profilept_PT
dc.titleSea cucumber Holothuria forskali, a new resource for aquaculture? Reproductive biology and nutraceutical approachpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage17pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleAquaculture Researchpt_PT
person.familyNamePinteus
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person.familyNameTecelão
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person.givenNameSusete
person.givenNameJoana
person.givenNameCelso
person.givenNameCarla
person.givenNameRui
person.givenNameAna
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person.identifier.ridB-3366-2017
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rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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