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Influence of Aloe vera on water absorption and enzymatic in vitro degradation of alginate hydrogel films

2013-10Artigo científico Acesso restrito
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datacite.subject.fosCiências Naturais::Ciências Biológicas
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorPereira, Rúben F.
dc.contributor.authorCarvalho, Anabela
dc.contributor.authorGil, M.H.
dc.contributor.authorMendes, Ausenda
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2026-03-24T15:44:16Z
dc.date.available2026-03-24T15:44:16Z
dc.date.issued2013-10
dc.description.abstractThis study investigates the influence of Aloe vera on water absorption and the in vitro degradation rate of Aloe vera-Ca-alginate hydrogel films, for wound healing and drug delivery applications. The influence of A. vera content (5%, 15% and 25%, v/v) on water absorption was evaluated by the incubation of the films into a 0.1 M HCl solution (pH 1.0), acetate buffer (pH 5.5) and simulated body fluid solution (pH 7.4) during 24 h. Results show that the water absorption is significantly higher for films containing high A. vera contents (15% and 25%), while no significant differences are observed between the alginate neat film and the film with 5% of A. vera. The in vitro enzymatic degradation tests indicate that an increase in the A. vera content significantly enhances the degradation rate of the films. Control films, incubated in a simulated body fluid solution without enzymes, are resistant to the hydrolytic degradation, exhibiting reduced weight loss and maintaining its structural integrity. Results also show that the water absorption and the in vitro degradation rate of the films can be tailored by changing the A. vera content.eng
dc.description.sponsorshipThe authors would like to thank ZeusQuímica Lda and Aloecorp Inc. for kindly supplying the Aloe vera used for this work and the support of the Portuguese Foundation for Science and Technology through the strategic project Pest-OE/EME/UI4044/2011.
dc.identifier.citationRúben F. Pereira, Anabela Carvalho, M.H. Gil, Ausenda Mendes, Paulo J. Bártolo, Influence of Aloe vera on water absorption and enzymatic in vitro degradation of alginate hydrogel films, Carbohydrate Polymers, Volume 98, Issue 1, 2013, Pages 311-320, ISSN 0144-8617, https://doi.org/10.1016/j.carbpol.2013.05.076.
dc.identifier.doi10.1016/j.carbpol.2013.05.076
dc.identifier.issn0144-8617
dc.identifier.urihttp://hdl.handle.net/10400.8/15970
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S0144861713005614?via%3Dihub
dc.relation.ispartofCarbohydrate Polymers
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAlginate
dc.subjectAloe vera
dc.subjectWound healing
dc.subjectWater absorption
dc.subjectIn vitro degradation
dc.titleInfluence of Aloe vera on water absorption and enzymatic in vitro degradation of alginate hydrogel filmseng
dc.typejournal article
dcterms.referenceshttp://dx.doi.org/10.1016/j. carbpol.2013.05.076
dspace.entity.typePublication
oaire.awardNumberPEst-OE/EME/UI4044/2011
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.endPage320
oaire.citation.issue1
oaire.citation.startPage311
oaire.citation.titleCarbohydrate Polymers
oaire.citation.volume98
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameBrás Pereira
person.familyNameMendes
person.familyNameBartolo
person.givenNameRúben Filipe
person.givenNameAusenda
person.givenNamePaulo
person.identifier1337969
person.identifier203086
person.identifier.ciencia-id9417-153E-4473
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-7255-3400
person.identifier.orcid0000-0003-3004-8972
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridP-8503-2018
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55421048100
person.identifier.scopus-author-id7102443940
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationeda35774-59b3-4801-aa88-9c20f4c31a78
relation.isAuthorOfPublication5ac3b700-95c6-4782-861a-deea8e449a7c
relation.isAuthorOfPublicationab44d1ae-46d0-45c2-b19f-200024b5a990
relation.isAuthorOfPublication.latestForDiscoveryeda35774-59b3-4801-aa88-9c20f4c31a78
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